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Figure 2 | BMC Cancer

Figure 2

From: The spectrum of resistance in SR/CR mice: the critical role of chemoattraction in the cancer/leukocyte interaction

Figure 2

Naïve SR/CR pups resist the initial challenge with EL-4 and J774. Pups from an SR/CR × WT cross were challenged with 10e6 EL-4 prior to being challenged with any other cancer cell line and 22 out of 35 pups survived. Pups from an SR/CR × WT cross that were challenged with 5 × 10e5 and a second challenge with 5 × 10e6 S180 have a historical survival rate of ~30% [1, 2]. When nine pups from an SR/CR × WT cross were challenged with 5 × 10e4 J774 prior to being challenged with any other cell line, one mouse survived. All WT mice challenged with EL-4, S180, and J774 at the indicated doses uniformly died. Mice were monitored for at least 60 days after challenge.

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