Table 4 SOCS 4 - 7 Mean mRNA expression levels
Patient and tumour characteristics | SOCS4 Mean (SD) | P | SOCS5 Mean (SD) | P | SOCS6 Mean (SD) | P | SOCS7 Mean (SD) | P |
|---|---|---|---|---|---|---|---|---|
ER Status | ||||||||
   ER(-) vs. ER(+) | 198 (834) vs. 296 (1035) | 0.63 | 1669 (2950) vs. 1066 (2215) | 0.25 | 450 (1209) vs. 2018 (5905) | 0.13 | 2310 (8080) vs. 715 (1341) | 0.11 |
Tumor Grade | ||||||||
   Grade 1 vs. 2 | 142 (540) vs. 554 (1468) | 0.13 | 834 (2468) vs. 2164 (3270) | 0.09 | 2110 (7427) vs. 968 (2171) | 0.51 | 5459 (14250) vs. 1396 (2583) | 0.22 |
   Grade 1 vs. 3 | 142 (540) vs. 113 (380) | 0.82 | 834 (2468) vs. 2076 (5191) | 0.17 | 2110 (7427) vs. 475 (1267) | 0.34 | 5459 (14250) | 0.13 |
   Grade 2 vs. 3 | 554 (1468) vs. 113 (380) | 0.07 | 2164 (3270) vs. 2076 (5191) | 0.92 | 968 (2171) vs. 475 (1267) | 0.21 | vs. 427 (1339) 1396 (2583) vs. 427 (1339) | 0.037 |
NPI | ||||||||
   NPI 1 vs. 2 | 276 (1004) vs. 168 (513) | 0.49 | 1742(2846) vs. 1715 (3064) | 0.97 | 1117 (4564) vs. 687 (1610) | 0.51 | 2740 (8754) vs. 518 (1189) | 0.06 |
   NPI 1 vs. 3 | 276 (1004) vs. 419 (1441) | 0.72 | 1742 (2846) vs. 3132 (9006) | 0.56 | 117 (4564) vs. 439 (1138) | 0.31 | 2740 (8754) vs. 538 (1125) | 0.07 |
   NPI 2 vs. 3 | 168 (513) vs. 419 (1441) | 0.52 | 1715 (3064) vs. 3132 ( 9006) | 0.56 | 687 (1610) vs. 439 (1138) | 0.53 | 518 (1189) vs. 538 (1125) | 0.95 |
TNM | ||||||||
   TNM 1 vs. 2 | 384 (1208) vs. 180 (532) | 0.25 | 1856 (3095) vs. 2328 (6035) | 0.66 | 552 (1217) vs. 1925 (5786) | 0.16 | 2239 (7923) vs. 1329 (4566) | 0.47 |
   TNM 1 vs. 3 | 384(1208) vs. 75 (198) | 0.08 | 1856 (3095) vs. 1521(3114) | 0.8 | 552 (1217) vs. 93 (217) | 0.01 | 2239 (7923) vs. 137 (353) | 0.04 |
   TNM 1 vs. 4 | 384 (1208) vs. 1.5 (3) | 0.02 | 1856 (3095) vs. 0.26 (0.53) | 0.00 | 552 (1217) vs. 156 (33.7) | 0.001 | 2239 (7923) vs. 0.004 (0.008) | 0.03 |
   TNM 2 vs. 3 | 180 (532) vs. 75 (198) | 0.37 | 2328 (6035) vs. 1521 (3114) | 0.61 | 1925 (5786) vs. 93 (217) | 0.06 | 1329 (4566) vs. 137 (353) | 0.13 |
   TNM 2 vs. 4 | 180 (532) vs. 1.5 (3) | 0.049 | 2328 (6035) vs. 0.26( 0.53) | 0.03 | 1925 (5786) vs. 22.8 (33.7) | 0.05 | 1329 (4566) vs. 0.004 (0.008) | 0.09 |
   TNM 3 vs. 4 | 75 (198) vs. 1.5 (3) | 0.36 | 1521 (3114) vs. 0.26 (0.53) | 0.24 | 93 (217) vs. 22.8 (33.7) | 0.43 | 137 (353) vs. 0.004 (0.008) | 0.35 |
Survival | ||||||||
   DF vs. LR | 146 (566) vs. 959 (2223) | 0.37 | 1551 (2851) vs. 1807 (2315) | 0.79 | 994 (3987) vs. 776 (1311) | 0.75 | 2110 (7490) vs. 271 (716) | 0.04 |
   DF vs. DR | 146 (566) vs. 2.1 (3.3) | 0.024 | 1551 (2851) vs. 10190 (14338) | 0.25 | 994 (3987) vs. 372 (582) | 0.23 | 2110 (7490) vs. 246 (500) | 0.03 |
   DF vs. D | 146 (566) vs. 685 (1577) | 0.23 | 1551 (2851) vs. 1190 (2787) | 0.66 | 994 (3987) vs. 825 (1967) | 0.81 | 2110 (7490) vs. 467 (1232) | 0.07 |