Table 3 SOCS 1 - 3 Mean mRNA expression levels
Patient and tumour characteristics | SOCS1 Mean (SD) | P | SOCS2 Mean (SD) | P | SOCS3 Mean (SD) | P |
|---|---|---|---|---|---|---|
ER Status | ||||||
   ER(-) vs. ER(+) | 47(165) vs. 18.4(38.4) | 0.18 | 329585 (1361524) vs. 241896 (1097499) | 0.72 | 0.6 (3.1) vs. 3.2 (10.7) | 0.16 |
Tumor Grade | ||||||
   Grade 1 vs. 2 | 90(189) vs. 41(163) | 0.33 | 335817 (1426927) vs. 44859 (128040) | 0.37 | 4 (13.5) vs. 0.8 (4.1) | 0.32 |
   Grade 1 vs. 3 | 90(189) vs. 10.3(53.6) | 0.08 | 335817 (1426927) vs. 512760 (1654661) | 0.65 | 4 (13.5) vs. 0.7 (3.1) | 0.3 |
   Grade 2 vs. 3 | 41(163) vs. 10.3(53.6) | 0.26 | 44859 (128040) vs. 512760 (1654661) | 0.04 | 0.8(4.1) vs. 0.7 (3.1) | 0.9 |
NPI | ||||||
   NPI 1 vs. 2 | 20.1(86.4) vs. 51(178) | 0.32 | 495133 (1685902) vs. 66274 (241181) | 0.06 | 1.2 (7.7) vs. 2.1 (6) | 0.52 |
   NPI 1 vs. 3 | 20.1(86.4) vs. 58(148) | 0.35 | 495133 (1685902) vs. 12414 (25254) | 0.03 | 1.2 (7.7) vs. 0.1 (0.2) | 0.26 |
   NPI 2 vs. 3 | 51(178) vs. 58(148) | 0.88 | 66274 (241181) vs. 12414 (25254) | 0.18 | 2.1 (6) vs. 0.1 (0.2) | 0.04 |
TNM | ||||||
   TNM 1 vs. 2 | 53(170) vs. 20.5(67.1) | 0.19 | 157325 (679157) vs. 364680 (1454925) | 0.42 | 1.9 (8.4) vs. 0.9 (3.6) | 0.79 |
   TNM 1 vs. 3 | 53(170) vs. 5.7(13) | 0.039 | 157325 (679157) vs. 1180151 (3122352) | 0.42 | 1.9 (8.4) vs. 0.3 (0.9) | 0.17 |
   TNM 1 vs. 4 | 53(170) vs. 3.2(5.3) | 0.027 | 157325 (679157) vs. 3256 (6508) | 0.08 | 1.9 (8.4) vs. 0.2 (0.2) | 0.12 |
   TNM 2 vs. 3 | 20.5(67) vs. 5.7(13) | 0.23 | 364680 (1454925) vs. 1180151 (3122352) | 0.52 | 0.9 (3.6) vs. 0.3 (0.9) | 0.39 |
   TNM 2 vs. 4 | 20.5(67) vs. 3.2(5.3) | 0.13 | 364680 (1454925) vs. 3256 (6508) | 0.14 | 0.9(3.6) vs. 0.2 (0.2) | 0.23 |
   TNM 3 vs. 4 | 5.7(13) vs. 3.2(5.3) | 0.67 | 1180151(3122352) vs. 3256 (6508) | 0.36 | 0.3(0.9) vs. 0.2 (0.2) | 0.68 |
Survival | ||||||
   DF vs. LR | 48(154) vs. 1.2(3.2) | 0.007 | 360706 (1370000) vs. 3499 (9061) | 0.02 | 1.5 (7.3) vs. 0.8 (2.1) | 0.55 |
   DF vs. DR | - | - | 360706 (1370000) vs. 3897(8714) | 0.02 | - | - |
   DF vs. D | 48(154) vs. 7.4(13.3) | 0.02 | 360706 (1370000) vs. 27239 (81017) | 0.03 | 1.5 (7.3) vs. 0.4 (1.1) | 0.22 |