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Table 2 DAVID information

From: Meta-analysis of archived DNA microarrays identifies genes regulated by hypoxia and involved in a metastatic phenotype in cancer cells

 

Pathways

Databases

Genes

Cancer

Prostate cancer

KEGG

MAPK1, IGF1, MAP2K1, CCNE2, NFKBIA

 

Chronic myeloid leukemia

KEGG

MAPK1, MAP2K1, NFKBIA

 

Colorectal cancer

KEGG

FOS, MAPK1, MAP2K1

 

Renal cell carcinoma

KEGG

VEGFA, MAPK1, MAP2K1, PAK6

 

Pancreatic cancer

KEGG

STAT1, VEGFA, MAPK1, MAP2K1

 

Bladder cancer

KEGG

VEGFA, MAPK1, MAP2K1

 

Glioma

KEGG

MAPK1, IGF1, MAP2K1

 

Melanoma

KEGG

MAPK1, IGF1, MAP2K1

Proliferation and cell motility

Focal adhesion

KEGG

FLNC, VEGFA, MAPK1, SPP1, IGF1, MAP2K1, PAK6, LAMA3, MYL9

 

MAPK signalling pathway

KEGG, BIOCARTA

FLNC, NR4A1, FOS, MAPK1, DUSP1, MAP2K1, DUSP8, NFKBIA

 

VEGF signalling pathway

KEGG

VEGFA, HSPB1, MAPK1, MAP2K1

 

ErbB signalling pathway

KEGG

MAPK1, MAP2K1, PAK6, ERBB3

 

Regulation of actin cytoskeleton

KEGG

ACTG2, MAPK1, MAP2K1, ACTC1, PAK6, MYL9

Pathogen recognition and phagocytosis

Pathogenic Escherichia coli infection - EPEC

KEGG

YWHAZ, TUBB2B, TUBB2A, TUBB2C, TUBB4

 

Pathogenic Escherichia coli infection - EHEC

KEGG

YWHAZ, TUBB2B, TUBB2A, TUBB2C, TUBB4

 

T Cell Receptor Signalling Pathway

BIOCARTA

FOS, MAP2K1, NFKBIA

 

Toll-like receptor signalling pathway

KEGG

STAT1, FOS, MAPK1, SPP1, MAP2K1, NFKBIA

 

fMLP induced chemokine gene expression in HMC-1 cells

BIOCARTA

MAPK1, MAP2K1, NFKBIA

 

Fc Epsilon Receptor I Signalling in Mast Cells

BIOCARTA

FOS, MAPK1, MAP2K1

Other

Keratinocyte Differentiation

BIOCARTA

MAPK1, MAP2K1, NFKBIA

 

Gap junction

KEGG

TUBB2B, MAPK1, MAP2K1, TUBB2A, TUBB2C, TUBB4

 

NFAT and Hypertrophy of the heart

BIOCARTA

MAPK1, IGF1, MAP2K1

 

Long-term depression

KEGG

MAPK1, IGF1, MAP2K1

 

Cadmium induces DNA synthesis and proliferation in macrophages

BIOCARTA

FOS, MAPK1, MAP2K1, NFKBIA

  1. DAVID classified 179 of the 183 genes of interest into 24 pathways from KEGG or Biocarta. Column 3 presents the genes involved in each specific pathway.