Vascular endothelial growth factor C promotes cervical cancer metastasis via up-regulation and activation of RhoA/ROCK-2/moesin cascade

Table 1 Clinicopathological associations of moesin expression in patients with cervical cancer

		Moesin immunostaining
	Total number of cases	-	+	++	+++
Normal cervical tissues (NC)	20	8 (40%)	11 (55%)	1 (5%)	0 (0%)
cervical intraepithelial neoplasia (CIN)	24	2 (8.3%)	18 (75%)	3 (12.5%)	1 (4.2%)
Cervical squamous carcinoma	42	4 (9.5%)	13 (31%)	15 (35.7%)	10 (23.8%)
stage I (SC(I))	22	2	8	8	4
stage II (SC(II))	20	2	5	7	6
Lymph node metastasis
With	10	0	1	2	7
Without	32	4	12	13	3

NOTE: Interpretation of moesin staining was described in Materials and Methods. Moesin staining was graded as negative (-; score: 0-1), weak (+; 2-4), moderate (++; 5-8), and strong (++; 9-12).

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