Clinical significance of Phosphatidyl Inositol Synthase overexpression in oral cancer

BMC Cancer

Table 1 Analysis of PI Synthase protein expression in normal oral tissues, OLs and OSCCs: Correlation with clinicopathological parameters and tobacco consumption habits

Clinicopathological parameters	Total Cases	PI Synthase cytoplasmic positivity
	N	n	(%)
Normal Oral tissues (N)	10	0
OLs	20	16	80
Differentiation
OLs w/o dysplasia	15	11	73
Dysplasia	5	5	100
Mild	2	2
Moderate	2	2
Severe	1	1
^Habits
^Non Tobacco consumer	2	2
^Tobacco consumer	10	8
^#Tobacco chewer	9	8
^#Khaini (Tobacco with lime)	4	4
^#Gutkha	2	3
^#Betel Quid with tobacco	5	4
^#Tobacco smoking	4	4
^#Alcohol	3	3
OSCCs	70	61	87
Differentiation ^a
WDSCC	25	19	76
MDSCC	40	38	95
PDSCC	5	4	80
^Habits ^b
^Non Tobacco consumer	4	2
^Tobacco consumer	17	17
^#Tobacco chewer	16	5
^#Khaini (Tobacco with lime)	14	14
^#Gutkha	-	-
^#Betel Quid with tobacco	2	2
^#Tobacco smoking	4	4
^#Alcohol	4	3

^#Overlapping habits; ^cases excluding TMA
a:WDSCC Vs MDSCC + PDSCC (p = 0.005); b: tobacco consumer Vs non-consumer (p = 0.03, OR = 9.0)

ISSN: 1471-2407