Figure 2From: Increased Rac1 activity and Pak1 overexpression are associated with lymphovascular invasion and lymph node metastasis of upper urinary tract cancer Immunohistochemistry for Rac1 (upper panel) and Pak1 (lower panel) proteins in Grade 3 carcinoma. Cytosolic compartments shows intensely brown staining in most of the cancer cells, displaying high Rac1 and Pak1 protein levels, but the nuclei of the cancer cells shows very weak staining.Back to article page