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Figure 2 | BMC Cancer

Figure 2

From: Breast cancer cell lines carry cell line-specific genomic alterations that are distinct from aberrations in breast cancer tissues: Comparison of the CGH profiles between cancer cell lines and primary cancer tissues

Figure 2

The average number of DNA copy number gain, loss and amplification for cell lines (n = 24) and the tumor tissues (n = 35). The average number of clones with copy number gain is and 651.7 ± 148.8 and 424.2 ± 215.9 in the cell lines and tumor tissues, respectively. The average number of clones with copy number loss is 1180.7 ± 433.8 and 548.0 ± 324.7 in the cell lines and tumor tissues, respectively. The average number of amplification clones is 41.3 ± 29.9 and 15.9 ± 18.6 in the tumor tissues and the cell lines, respectively. The difference is statistically significant (P = 0.012). White columns; the average number of DNA copy number gain. Gray columns; the average number of DNA copy number loss. Black columns; the average number of amplifications. Black bars; standard deviations. Ordinate; frequency of DCNA for each BAC clone, abscissa; samples.

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