Table 3 Risk of NPC associated with MDM2 genotypes by TP53 genotypes.
Genotype | Cases | Controls | OR* (95% CI) | |
|---|---|---|---|---|
MDM2309T>G | TP5372Arg>Pro | no. (%) | no. (%) | Â |
TT | Arg/Arg | 24 (4.6) | 68 (9.6) | 1.00 (reference) |
| Â | Arg/Pro | 63 (12.1) | 128 (18.0) | 1.34 (0.75-2.48) |
| Â | Pro/Pro | 24 (4.6) | 42 (5.9) | 1.63 (0.81-3.42) |
TG | Arg/Arg | 54 (10.3) | 120 (16.9) | 1.30 (0.72-2.39) |
| Â | Arg/Pro | 132 (25.3) | 168 (23.6) | 2.12 (1.90-3.86) |
| Â | Pro/Pro | 57 (10.9) | 58 (8.1) | 2.91 (1.53-5.31) |
GG | Arg/Arg | 39 (7.5) | 38 (5.3) | 2.83 (1.33-5.90) |
| Â | Arg/Pro | 75 (14.4) | 70 (9.8) | 3.13 (1.61-5.94) |
| Â | Pro/Pro | 54 (10.3) | 20 (2.8) | 7.75 (3.53-17.58) |