Variables | n | Estimated survival rates (%) | p-valuea | |
---|---|---|---|---|
5 years | 10 years | |||
Tumor thickness | 0.001 | |||
≤2.0 mm | 48 | 80 | 77 | |
2.1-4.0 mm | 73 | 76 | 59 | |
>4.0 mm | 81 | 49 | 43 | |
Tumor ulceration | 0.001 | |||
absent | 114 | 77 | 68 | |
present | 83 | 54 | 44 | |
Clark's level | <0.001 | |||
II - IV | 166 | 72 | 62 | |
V | 35 | 40 | 32 | |
Vascular infiltration | <0.001 | |||
absent | 162 | 73 | 61 | |
present | 40 | 39 | 39 | |
Tumor necrosis | <0.001 | |||
absent | 142 | 76 | 64 | |
present | 57 | 39 | 36 | |
Mitotic count (no./mm2) | 0.008 | |||
<1.7b | 35 | 84 | 84 | |
≥1.7 | 164 | 62 | 51 | |
Ki-67 (% pos) | <0.0001 | |||
≤16b | 49 | 89 | 86 | |
>16 | 138 | 57 | 47 | |
PHH3 (% pos) | ns | |||
≤0.8c | 56 | 67 | 47 | |
>0.8 | 55 | 57 | 50 | |
MCM4 (% pos) | ns | |||
≤40.7c | 48 | 61 | 43 | |
>40.7 | 48 | 58 | 46 | |
Mitosin (SId) | ns | |||
lowb | 45 | 58 | 47 | |
high | 58 | 59 | 42 |