Skip to main content

Table 2 Mitotic count and Ki-67 in association with expression of PHH3, MCM4 and mitosin

From: Ki-67 expression is superior to mitotic count and novel proliferation markers PHH3, MCM4 and mitosin as a prognostic factor in thick cutaneous melanoma

 

Mitotic count

 

Ki-67

 
 

(no./mm2)

 

(% pos)

 
 

median

p-valuea

median

p-valuea

PHH3 (% pos)

 

0.003

 

0.002

   ≤0.8b

3.4

 

26.0

 

   >0.8

8.9

 

36.0

 

MCM4 (% pos)

 

0.002

 

0.001

   ≤40.7b

5.1

 

26.0

 

   >40.7

11.1

 

37.5

 

Mitosin (SId)

 

ns

 

ns

   lowc

9.4

 

34.5

 

   high

7.7

 

31.5

 
  1. aMann-Whitney test
  2. bCut-off point median
  3. cCut-off point lower quartile
  4. dAbbreviation: SI, staining index