From: Ki-67 expression is superior to mitotic count and novel proliferation markers PHH3, MCM4 and mitosin as a prognostic factor in thick cutaneous melanoma
Mitotic count
Ki-67
(no./mm2)
(% pos)
median
p-valuea
PHH3 (% pos)
0.003
0.002
≤0.8b
3.4
26.0
>0.8
8.9
36.0
MCM4 (% pos)
0.001
≤40.7b
5.1
>40.7
11.1
37.5
Mitosin (SId)
ns
lowc
9.4
34.5
high
7.7
31.5