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Table 2 Mitotic count and Ki-67 in association with expression of PHH3, MCM4 and mitosin

From: Ki-67 expression is superior to mitotic count and novel proliferation markers PHH3, MCM4 and mitosin as a prognostic factor in thick cutaneous melanoma

  Mitotic count   Ki-67  
  (no./mm2)   (% pos)  
  median p-valuea median p-valuea
PHH3 (% pos)   0.003   0.002
   ≤0.8b 3.4   26.0  
   >0.8 8.9   36.0  
MCM4 (% pos)   0.002   0.001
   ≤40.7b 5.1   26.0  
   >40.7 11.1   37.5  
Mitosin (SId)   ns   ns
   lowc 9.4   34.5  
   high 7.7   31.5  
  1. aMann-Whitney test
  2. bCut-off point median
  3. cCut-off point lower quartile
  4. dAbbreviation: SI, staining index