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Table 1 Parameters of microtubule dynamics in MC+1 and MP6.1 cells

From: Tubulin binding cofactor C (TBCC) suppresses tumor growth and enhances chemosensitivity in human breast cancer cells

Parameters

 

MP6.1

MC+1

Change

Mean rate (μm/min ± SE)

Growth

16.41 ± 1.99

10.54 ± 0.37 *

-36%

 

Shortening

15.25 ± 2.14

14.35 ± 1.53

 

Mean length (μm ± SE)

Growth

2.38 ± 0.49

2.14 ± 0.51

 
 

Shortening

2.40 ± 0.39

2.29 ± 0.10

 

Mean duration (min ± SE)

Growth

0.15 ± 0.02

0.22 ± 0.01 *

47%

 

Shortening

0.16 ± 0.01

0.17 ± 0.01

 
 

Pause

0.25 ± 0.01

0.37 ± 0.02 *

48%

Mean frequency (min-1± SE)

Rescue

9.20 ± 0.53

14.20 ± 0.24 *

54%

 

Catastrophe

4.64 ± 0.70

5.38 ± 0.56

 

Dynamicity (μm/min ± SE)

 

8.80 ± 1.02

6.09 ± 1.06 *

-31%

  1. *: Values differ significantly from MP6.1 at ≥ 95% confidence level by Student's t-test. Values are represented as mean ± SD