From: Rac1 and Cdc42 are regulators of HRasV12-transformation and angiogenic factors in human fibroblasts
Genes up-regulated | Â | Â |
---|---|---|
Name | Fold Change | Reference |
Ubiquitin Conjugating enzyme 12 (UBC12) * | 6.4 | [39] |
Elongation factor-1 alpha-2 * | 2.3 | [40] |
Guanine nucleotide-binding regulatory protein (G-y-alpha) | 2.2 | Â |
mSin3A associated polypeptide p30 * | 2.1 | [41] |
Rac protein kinase alpha | 1.8 | Â |
Coupling protein G(s) alpha-subunit (alpha-S1) | 1.8 | Â |
Histone H1x | 1.8 | Â |
80K-L protein * | 1.6 | [42] |
Killer cell lectin-like receptor, Subfam. C, member 2 (NKG2C) * | 1.6 | [43] |
Alpha subunit of GsGTP binding protein | 1.5 | Â |
Lipoprotein-associated coagulation inhibitor (LACI) | 1.5 | Â |
ATP synthase alpha subunit | 1.3 | Â |
Heat shock protein 70 (hsp70) * | 1.3 | [44] |
Genes down-regulated | Â | Â |
Name | Fold Change | Â |
Insulin-like growth factor-binding protein-3 * | -1.9 | [45] |
28s Ribosomal RNA gene | -1.6 | Â |
Cyclooxygenase-2 (hCox-2) * | -1.6 | [46] |
Vascular endothelial growth factor (VEGF) * | -1.6 | [47] |
Urokinase plasminogen activator (uPA) * | -1.5 | [48] |
Human KIAA0628 | -1.5 | Â |
Asparagine synthetase | -1.5 | Â |
Axl tyrosine kinase receptor * | -1.5 | |
High mobility group isoform C (HMGI-C) * | -1.5 | |
Lnk adaptor protein | -1.4 | Â |
GTPase-activating protein ras p21 (RASA) | -1.4 | Â |
Human KIAA0728 protein | -1.3 | Â |
Axl tyrosine kinase receptor splice 2 * | -1.3 | |
N-myristoyltransferase 2 | -1.3 | Â |
Caveolin 2 * | -1.3 | [55] |
Glycosylphosphatidylinositol-H (GPI-H) | -1.3 | Â |