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Table 1 Growth Curve Analysis (doubling time in hrs)

From: Rac1 and Cdc42 are regulators of HRasV12-transformation and angiogenic factors in human fibroblasts

Cell Line (+) Tet - GENE OFF (-) Tet - GENE ON
MSU-1.1 30.2 (± 1.0) 29.8 (± 0.7)
PH3 MT 19.9 (± 0.5) 19.4 (± 0.7)
Vector Control 16.6 (± 0.5) 20.4 (± 1.2)*
Cdc42N17-C1 17.5 (± 2.0) 28.1 (± 2.0)**
Cdc42N17-C2 17.0 (± 1.7) 26.6 (± 1.2)**
Rac1N17-C1 16.3 (± 0.2) 31.2 (± 3.0)*
Rac1N17-C2 16.6 (± 0.7) 31.4 (± 1.0)**
Rac1N17/Cdc42N17 18.2 (± 0.5) 35.8 (± 1.2)*
  1. Values represent Mean ± SD
  2. *,** represent a significant difference compared to (-) Tet condition using a homoscedastic
  3. two-tailed t-test (p < 0.05, p < 0.01, respectively), N = 3 for all conditions