Figure 3

GO Classification of genes found by RIP CHIP of potential HuR targets and their relationship to the Acquired Capabilities of Cancer Model. A. Differentially expressed genes which are more represented in the Biological Processes (BP) GO category than expected. B. Original representation showing subsets of transcripts found to be targets of association with HuR (normal type). New transcripts found in this study with RIP-Chip (bold type). Enhanced expression upon binding to HuR influences several of the acquired capabilities of cancer cells described by Hanahan and Weinberg [23, 24].