Skip to main content
Figure 6 | BMC Cancer

Figure 6

From: Cancer resistance of SR/CR mice in the genetic knockout backgrounds of leukocyte effector mechanisms: determinations for functional requirements

Figure 6

Adoptive Transfers of SR/CR Nos2 Knockout Macrophages and Neutrophils are Less Protective. Thioglycolate elicited SR/CR macrophages and neutrophils were adoptively transferred into WT RAG1-/- mice. The WT RAG1-/- recipients were challenged the following day with S180, and their survival was monitored. Survival of SR/CR Nos2-/- recipients was intermediate, indicating that nitric oxide was one of the effector mechanisms used by SR/CR macrophages and neutrophils to kill cancer.

Back to article page