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Figure 4 | BMC Cancer

Figure 4

From: Cancer resistance of SR/CR mice in the genetic knockout backgrounds of leukocyte effector mechanisms: determinations for functional requirements

Figure 4

SR/CR Mice Do Not Require Nitric Oxide to Survive S180 Challenges. SR/CR mice were bred into the inducible nitric oxide synthase (Nos2) knockout background. Progeny that survived two challenges with S180, remaining healthy and cancer free, were considered resistant. Similar survival rates were seen for the BC Nos2+/- and Nos2-/-; however, there was a strong trend that the males were more cancer sensitive.

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