Bone invading NSCLC cells produce IL-7: mice model and human histologic data

BMC Cancer

Table 1 mouse groups and human biopsies summary data

	Survivorship	Bone metastatic invasion	Intensity of IL-7 staining	Metastasis in lung tissue
Control	5/6 (83%)	0	+ (stromal cells)	0
Group #1	5/6 (83%)	4/5	+++ (tumor cells and stromal cells)	micro- metastasis 1/5
Group #2	6/6 (100%)	0	+ (stromal cells)	0
10 Human biopsies	-	10/10	+++	-

Control indicates mice subjected only to bone implant; group #1 indicates mice injected with A549 cells close to the bone implant; group #2 indicates mice injected with A549 cells in the opposite flank to the bone implant.

ISSN: 1471-2407