p16 expression | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
 |  | neg | % | weak | % | mod | % | strong | % | P |
HPV | - | 14 | 60.9 | 10 | 90.9 | 12 | 66.7 | 24 | 63.2 | 0.325 |
 | + | 9 | 39.1 | 1 | 9.1 | 6 | 33.3 | 14 | 36.8 |  |
MSI | MSS | 19 | 86.4 | 11 | 100.0 | 17 | 94.4 | 37 | 97.4 | 0.266 |
 | MSI | 3 | 22.6 | 0 | 0.0 | 1 | 5.6 | 1 | 2.6 |  |
age (median) | Â | 63 | Â | 70 | Â | 66 | Â | 65 | Â | 0.344 |
gender | male | 10 | 43.5 | 7 | 63.6 | 12 | 66.7 | 21 | 55.3 | 0.466 |
 | female | 13 | 56.5 | 4 | 36.4 | 6 | 33.3 | 17 | 44.7 |  |
lymph nodes | - | 9 | 60.0 | 6 | 66.7 | 6 | 66.7 | 24 | 68.6 | 0.951 |
 | + | 6 | 40.0 | 3 | 33.3 | 12 | 33.3 | 11 | 31.4 |  |
grade of differentiation | good | 12 | 54.5 | 7 | 63.6 | 8 | 44.4 | 18 | 51.4 | 0.875 |
 | moderate | 7 | 31.8 | 3 | 27.3 | 9 | 50.0 | 13 | 37.1 |  |
 | poor | 3 | 13.6 | 1 | 9.1 | 1 | 6.6 | 4 | 11.4 |  |
location | proximal | 16 | 69.6 | 2 | 18.2 | 4 | 22.2 | 8 | 22.2 | 0.002 |
 | distal | 2 | 8.7 | 3 | 27.3 | 9 | 50.0 | 16 | 44.4 |  |
 | rectum | 5 | 21.7 | 6 | 54.5 | 5 | 27.8 | 12 | 33.3 |  |
stage | I | 3 | 13.0 | 4 | 40.0 | 2 | 11.8 | 4 | 10.8 | 0.066 |
 | II | 8 | 34.8 | 2 | 20.0 | 4 | 23.5 | 18 | 48.6 |  |
 | III | 10 | 43.5 | 4 | 40.0 | 6 | 35.3 | 13 | 35.1 |  |
 | IV | 2 | 8.7 | 0 | 0.0 | 5 | 29.4 | 2 | 5.4 |  |
adjuvant therapy | no | 6 | 30.0 | 6 | 75.0 | 5 | 33.3 | 15 | 55.6 | 0.186 |
 | yes | 14 | 70.0 | 2 | 25.0 | 10 | 66.7 | 12 | 44.4 |  |