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Table 2 Possible associations between HPV and clinicopathological parameters of colon cancer

From: Detection of HPV and the role of p16INK4Aoverexpression as a surrogate marker for the presence of functional HPV oncoprotein E7 in colorectal cancer

  

-

HPV

%

+

%

 

MSI

MSS

187

94.4

31

93.9

1

 

MSI

11

5.6

2

6.1

 

age (median)

 

56

 

60

 

0.05

gender

male

119

59.8

23

69.7

0.337

 

female

80

40.2

10

30.3

 

grade of differentiation

good

83

44.1

12

40.0

0.764

 

average

87

46.8

16

53.3

 
 

poor

17

9.0

2

6.7

 

location

proximal

57

30.3

13

39.4

0.565

 

distal

70

37.2

10

30.3

 
 

rectum

61

32.4

10

30.3

 

lymph nodes

+

97

86.6

82

89.1

0.670

 

-

15

13.4

10

10.9

 

stage

I

25

13.0

3

9.7

0.265

 

II

55

28.7

13

41.9

 
 

III

62

32.3

12

38.7

 
 

IV

50

26.0

3

9.7

 

adjuvant

yes

62

37.8

22

73.3

0.303

 

no

102

62.2

8

26.7

 
  1. Possible associations were investigated using the χ2-test or Fisher's exact test (when appropriate) for categorical variables and using Student t-test or Mann-Whitney U test (when appropriate) for continuous variables (MSI: microsatellite instability, MSS: microsatellite stability)