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Table 1 Histopathological characteristics of breast cancers and normal healthy controls

From: Differential profiling of breast cancer plasma proteome by isotope-coded affinity tagging method reveals biotinidase as a breast cancer biomarker

Characteristics

Discovery by ICAT & qualification

Verification in a blinded set

Normal healthy control

  

   No. cases

6

21

   Age (median)

36-51(49.5)

17-49 (35)

Breast cancer

  

   No. cases

6

21

   Age (median)

36-51 (49.5)

36-78 (50)

   Histological grade

Grade 1 (2), Grade 2 (2), Grade 3 (2)

Grade 0 (5), Grade 1 (4), Grade 2 (9), Grade 3 (2), Grade 4 (1)

   Tumor size

T1 (3), T2 (3)

T0 (6), T1 (6), T2 (8), T3 (1)

   Lymph node status

N0 (4), N2 (1), N3 (1)

N0 (12), N1 (7), N2 (2)

   Metastasis

M0 (6)

M0 (20), M1(1)

   Estrogen receptor

Negative (6)

Negative (10), Positive (10)*

   Progesterone receptor

Negative (6)

Negative (12), Positive (8)*

  1. * Receptor type for one breast cancer patient was not determined.