Figure 5
From: XIAP is not required for human tumor cell survival in the absence of an exogenous death signal
Effect of XIAP depletion on tumor cell viability and TRAIL sensitivity. XIAP depleted cells were exposed to TRAIL 40 hr following electroporation, and viability was measured 24 hr following TRAIL exposure Untreated cells (black circle); Electroporated cells (black square); 1 μM control siRNA (black triangle) 1 μM XIAP siRNA (inverted black triangle). Percent viability is expressed relative to untreated controls for each cell line. A similar result was obtained with the s1456 siRNA in SW620 cells (Additional File 2).