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Table 3 Expression of Prx, association with patient and tumor characteristics.

From: Specific expression profile and prognostic significance of peroxiredoxins in grade II-IV astrocytic brain tumors

Characteristic

PrxI

+/-

PrxII

+/-

PrxIII

+/-

PrxIV

+/-

PrxV

+/-

PrxVI

+/-

PATIENT

      

Age

      

   Mean

45.0/52.5

47.9/54.6

51.8/50.2

#/50.9

#/51.1

52.9/51.0

   Median

39.8/54.4

45.6/56.3

54.1/51.9

#/53.8

#/53.9

56.8/53.5

 

p = 0.014*

p = 0.005*

n.s.

  

n.s.

Sex

      

   Male

37/118

86/70

101/56

1/154

#/156

13/139

   Female

21/93

55/59

59/51

-/110

#/110

12/102

 

n.s.

n.s.

n.s.

n.s.

 

n.s.

Recurrences

      

   None

42/193

117/118

136/96

1/229

#/231

29/201

   ≥ 1

22/49

43/49

42/29

-/71

#/70

4/67

 

p = 0.015**

n.s.

n.s.

n.s.

 

n.s.

Tumor proliferation

(MIB-1)

      

   Mean

      

   SD

13.8/16.9

16.2/16.5

17.5/15.2

#/16.5

#/16.4

11.1/16.8

   Median

23.7/21.6

24.5/18.9

22.7/22.3

#/22.2

#/22.2

18.1/22.0

 

5.0/10.4

8.2/12.2

10.6/7.1

#/9.4

#/9.4

5.0/10.0

 

p = 0.019***

n.s.

p = 0.056****

  

p = 0.033***

Tumor

Apoptosis

      

   Mean

5.5/10.4

7.6/11.6

8.7/10.7

#/9.6

#/9.6

8.9/9.4

   SD

12.1/15.9

12.7/17.9

13.5/18.0

#/15.2

#/15.2

14.2/15.6

   Median

3.6/7.1

3.6/7.1

3.6/3.6

#/3.6

#/3.6

3.6/3.6

 

p < 0.001***

p = 0.007***

n.s.

  

n.s.

  1. * T-test, only primary tumors were included
  2. ** Chi-square test
  3. *** Mann-Whitney test
  4. **** Near-significant p-value by Mann-Whitney test
  5. # No cases in prx-positive group, analysis of significance not possible