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Table 3 Expression of Prx, association with patient and tumor characteristics.

From: Specific expression profile and prognostic significance of peroxiredoxins in grade II-IV astrocytic brain tumors

Characteristic PrxI
+/-
PrxII
+/-
PrxIII
+/-
PrxIV
+/-
PrxV
+/-
PrxVI
+/-
PATIENT       
Age       
   Mean 45.0/52.5 47.9/54.6 51.8/50.2 #/50.9 #/51.1 52.9/51.0
   Median 39.8/54.4 45.6/56.3 54.1/51.9 #/53.8 #/53.9 56.8/53.5
  p = 0.014* p = 0.005* n.s.    n.s.
Sex       
   Male 37/118 86/70 101/56 1/154 #/156 13/139
   Female 21/93 55/59 59/51 -/110 #/110 12/102
  n.s. n.s. n.s. n.s.   n.s.
Recurrences       
   None 42/193 117/118 136/96 1/229 #/231 29/201
   ≥ 1 22/49 43/49 42/29 -/71 #/70 4/67
  p = 0.015** n.s. n.s. n.s.   n.s.
Tumor proliferation
(MIB-1)
      
   Mean       
   SD 13.8/16.9 16.2/16.5 17.5/15.2 #/16.5 #/16.4 11.1/16.8
   Median 23.7/21.6 24.5/18.9 22.7/22.3 #/22.2 #/22.2 18.1/22.0
  5.0/10.4 8.2/12.2 10.6/7.1 #/9.4 #/9.4 5.0/10.0
  p = 0.019*** n.s. p = 0.056****    p = 0.033***
Tumor
Apoptosis
      
   Mean 5.5/10.4 7.6/11.6 8.7/10.7 #/9.6 #/9.6 8.9/9.4
   SD 12.1/15.9 12.7/17.9 13.5/18.0 #/15.2 #/15.2 14.2/15.6
   Median 3.6/7.1 3.6/7.1 3.6/3.6 #/3.6 #/3.6 3.6/3.6
  p < 0.001*** p = 0.007*** n.s.    n.s.
  1. * T-test, only primary tumors were included
  2. ** Chi-square test
  3. *** Mann-Whitney test
  4. **** Near-significant p-value by Mann-Whitney test
  5. # No cases in prx-positive group, analysis of significance not possible