Skip to main content

Table 5 Overall breast cancer survival in relation to serum concentrations of organochlorines by estrogen receptor status.

From: Organochlorine exposures influence on breast cancer risk and survival according to estrogen receptor status: a Danish cohort-nested case-control study

Organochlorines Estrogen receptor positive Estrogen receptor negative
in quartiles (ng/mL) Cases/control Adjusted RR (95% CI)a p trendb Cases/controls Adjusted RR (95% CI) p trend
HCB
I <206.50 13/15 1.0 ref.c   7/4 1.0  
II 206.50-269.75 15/14 0.7 (0.3-1.6)   8/3 0.9 (0.3-3.1)  
III 269.75-335.75 17/12 1.1 (0.5-2.4)   3/8 0.2 (0.0-1.2)  
IV >335.75 13/15 1.1 (0.5-2.5) >0.20 4/7 0.2 (0.1-1.7) 0.03
Dieldrin
I <12.01 8/21 1.0   4/7 1.0  
II 12.01-28.30 17/12 3.4 (1.3-8.7)   3/8 0.4 (0.1-3.1)  
III 28.30-57.11 17/12 2.6 (1.0-6.3)   7/4 1.9 (0.5-7.8)  
IV >57.11 17/12 2.2 (0.9-5.4) >0.20 8/3 1.8 (0.3-5.5) 0.06
ΣPCB
I <811.11 14/15 1.0   6/5 1.0  
II 811.11-1076.04 15/14 1.5 (0.6-3.4)   7/4 0.4 (0.1-1.6)  
III 1076.04-1405.73 13/16 1.0 (0.4-2.3)   5/6 0.5 (0.1-2.2)  
IV >1405.73 17/12 2.5 (1.1-5.7) >0.20 4/7 0.1 (0.0-5.6) 0.02
p,p'-DDE
I <741.04 15/14 1.0   6/5 1.0  
II 741.04-1129.75 13/16 0.7 (0.3-1.6)   4/7 0.3 (0.0-2.0)  
III 1129.75-1688.85 17/12 1.0 (0.5-2.2)   5/6 0.7 (0.1-3.7)  
IV >1688.85 14/15 1.0 (0.5-2.1) >0.20 7/4 0.3 (0.1-2.1) >0.20
  1. a Relative risk of dying, 95% confidence interval, adjusted for age at diagnosis, metastatic lymph nodes, and tumor size; b two sided p-value for linear trend in RR's; c Reference category. Cases with missing information on confounders were excluded.