Local and distant recurrences in rectal cancer patients are predicted by the nonspecific immune response; specific immune response has only a systemic effect - a histopathological and immunohistochemical study

Table 3 Results of the multivariate Cox regression analysis for the risk on local recurrence, distant metastases and survival for the presence of inflammatory infiltrate and TNM classification.

	local recurrence		distant metastases		2 year survival
	RR	95%CI	RR	95%CI	RR	95%CI
TNM I/II	1.0		1.0		1.0
TNM III/IV	4.8	2.7-8.8	2.8	2.2-3.7	5.8	4.1-8.3
none/few inflammatory cells	1.0		1.0		1.0
extensive inflammatory infiltrate	1.7	0.7-4.3	2.6	1.5-4.6	2.4	1.2-4.5

Median follow up is 19.6 months, n = 1416. RR: relative risk, Cl: confidence interval

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