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Table 3 Results of the multivariate Cox regression analysis for the risk on local recurrence, distant metastases and survival for the presence of inflammatory infiltrate and TNM classification.

From: Local and distant recurrences in rectal cancer patients are predicted by the nonspecific immune response; specific immune response has only a systemic effect - a histopathological and immunohistochemical study

  local recurrence distant metastases 2 year survival
  RR 95%CI RR 95%CI RR 95%CI
TNM I/II 1.0   1.0   1.0  
TNM III/IV 4.8 2.7-8.8 2.8 2.2-3.7 5.8 4.1-8.3
none/few inflammatory cells 1.0   1.0   1.0  
extensive inflammatory infiltrate 1.7 0.7-4.3 2.6 1.5-4.6 2.4 1.2-4.5
  1. Median follow up is 19.6 months, n = 1416. RR: relative risk, Cl: confidence interval