TY - JOUR AU - Tan, Dong-Feng AU - Huberman, Joel A. AU - Hyland, Andrew AU - Loewen, Gregory M. AU - Brooks, John SJ AU - Beck, Amy F. AU - Todorov, Ivan T. AU - Bepler, Gerold PY - 2001 DA - 2001/06/25 TI - MCM2 - a promising marker for premalignant lesions of the lung: a cohort study JO - BMC Cancer SP - 6 VL - 1 IS - 1 AB - Because cells progressing to cancer must proliferate, marker proteins specific to proliferating cells may permit detection of premalignant lesions. Here we compared the sensitivities of a classic proliferation marker, Ki-67, with a new proliferation marker, MCM2, in 41 bronchial biopsy specimens representing normal mucosa, metaplasia, dysplasia, and carcinoma in situ. SN - 1471-2407 UR - https://doi.org/10.1186/1471-2407-1-6 DO - 10.1186/1471-2407-1-6 ID - Tan2001 ER -