Figure 3
From: COL11A1 in FAP polyps and in sporadic colorectal tumors
Protein truncation test (PTT) on a) FAP adenoma samples, wt, wild type allele, mut, germline mutated allele, other bands indicate secondary mutations of either the wild type or the germline mutated allele. TP, polyp from transverse colon, DP, polyp from descending colon, RP, polyp from rectum, AN, normal FAP tissue taken from ascending colon. The marker CFA756 was used to approximate the size in KD (left), b) examples of sporadic colorectal carcinomas.