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Table 2 Number of cancer cases among subjects that subsequently became digitoxin users.

From: Digitoxin medication and cancer; case control and internal dose-response studies

ICD-10

Site

Sex

Digitoxin group

Control group

Odds Ratio (95% CI)

C50

Breast

F

275

232

1.19(1.11, 1.28)

C61

Prostate

M

370

296

1.25(1.08, 1.45)

C18–21

Colo-rectal

M+F

430

325

1.32(1.15, 1.52)

C32–34

Lung

M+F

163

112

1.46(1.15, 1.86)

C64,C65,C67,C68

Kidney, urinary

M+F

201

180

1.06(0.95, 1.17)

C43.C44

Melanoma, other skin

M+F

154

191

0.81 (0.66, 0.99)

C81–C85,C88–

Leukemia/Lymphoma

M+F

198

117

1.69(1.35,2.11)

C92

     

C00–C97

All sites

M+F

2435

2017

1.21 (1.15, 1.28)

  1. Number of cancer cases among subjects that subsequently became digitoxin users,and among matched controls.Digitoxin group=the cancer cases among the 9271 patients constituting the database just before the start on digitoxin medication. Control group=for each subject in the digitoxin group one control was randomly picked out from the general population. These controls were matched on birthday and gender and should be alive at the time when the corresponding digitoxin user started on digitoxin.