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  1. Content type: Research article

    Physician recommendations for colorectal cancer (CRC) screening have consistently been shown to be a strong predictor of screening. The aim of this study was to investigate perceptions of CRC screening modalit...

    Authors: Hye Young Shin, Mina Suh, Boyoung Park, Jae Kwan Jun and Kui Son Choi

    Citation: BMC Cancer 2017 17:860

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  2. Content type: Research article

    In a previous paper, we had assumed that the risk of screen-detected breast cancer mostly reflects inherent risk, and the risk of whether a breast cancer is interval versus screen-detected mostly reflects risk...

    Authors: Kavitha Krishnan, Laura Baglietto, Jennifer Stone, Catriona McLean, Melissa C. Southey, Dallas R. English, Graham G. Giles and John L. Hopper

    Citation: BMC Cancer 2017 17:859

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  3. Content type: Research article

    The significance of PLK1 (polo-like kinase 1) has become increasingly essential as both a biomarker and a target for cancer treatment. Here, we aimed to determine the downstream genes of PLK1 and their effects...

    Authors: Zhe Zhang, Guojun Zhang, Zhipeng Gao, Shiguang Li, Zeliang Li, Jianbin Bi, Xiankui Liu, Zhenhua Li and Chuize Kong

    Citation: BMC Cancer 2017 17:861

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  4. Content type: Research article

    Well-known anti-malarial drug artemisinin exhibits potent anti-cancerous activities. In-vivo and in-vitro studies showed its anti-tumor and immunomodulatory properties signifying it as a potent drug candidate ...

    Authors: Kanchan Kumari, Sunita Keshari, Debomita Sengupta, Surendra C. Sabat and Sandip K. Mishra

    Citation: BMC Cancer 2017 17:858

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  5. Content type: Research article

    Primary liver cancer is a lethal malignancy with a high mortality worldwide. Currently, sorafenib is the most effective molecular-targeted drug against hepatocellular carcinoma (HCC). However, the sorafenib re...

    Authors: Yinzong Xiao, Lunquan Sun, Yongming Fu, Yan Huang, Rongrong Zhou, Xingwang Hu, Pengcheng Zhou, Jun Quan, Ning Li and Xue-Gong Fan

    Citation: BMC Cancer 2017 17:857

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  6. Content type: Research article

    Histone demethylase JARID1B plays several context dependent roles in epigenetic regulation of cellular differentiation in normal development and is highly expressed in multiple human cancers. The protein is a ...

    Authors: Łukasz Kuźbicki, Dariusz Lange, Agata Stanek-Widera and Barbara W. Chwirot

    Citation: BMC Cancer 2017 17:854

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  7. Content type: Research article

    Compared with World Health Organization-defined acute myeloid leukaemia (AML) not otherwise specified, patients with AML with myelodysplasia-related changes (AML-MRC) are generally older and more likely to hav...

    Authors: John F. Seymour, Hartmut Döhner, Aleksandra Butrym, Agnieszka Wierzbowska, Dominik Selleslag, Jun Ho Jang, Rajat Kumar, James Cavenagh, Andre C. Schuh, Anna Candoni, Christian Récher, Irwindeep Sandhu, Teresa Bernal del Castillo, Haifa Kathrin Al-Ali, Jose Falantes, Richard M. Stone…

    Citation: BMC Cancer 2017 17:852

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  8. Content type: Case report

    Colorectal carcinoma (CRC) is one of the most common causes of cancer-related deaths. The mean age of patients with CRC ranges from 49 to 60 years. Pediatric CRC is unusual, which often escapes early diagnosis...

    Authors: Yung-Sung Yeh, Yu-Tang Chang, Cheng-Jen Ma, Ching-Wen Huang, Hsiang-Lin Tsai, Yi-Ting Chen and Jaw-Yuan Wang

    Citation: BMC Cancer 2017 17:849

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  9. Content type: Case report

    Pancreatic schwannoma is a rare tumor. Preoperative diagnosis of pancreatic schwannoma is challenging due to its tendency to mimic other lesions of the pancreas. We describe a case of pancreatic schwannoma and...

    Authors: Yuntong Ma, Bingqi Shen, Yingmei Jia, Yanji Luo, Yisu Tian, Zhi Dong, Wei Chen, Zi-Ping Li and Shi-Ting Feng

    Citation: BMC Cancer 2017 17:853

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  10. Content type: Debate

    Over the last decades numerous initiatives have been set up that aim at translating the best available medical knowledge and treatment into clinical practice. The inherent complexity of the programs and discre...

    Authors: Christoph Kowalski, Ullrich Graeven, Christof von Kalle, Hauke Lang, Matthias W. Beckmann, Jens-Uwe Blohmer, Martin Burchardt, Michael Ehrenfeld, Jan Fichtner, Stephan Grabbe, Hans Hoffmann, Heinrich Iro, Stefan Post, Anton Scharl, Uwe Schlegel, Thomas Seufferlein…

    Citation: BMC Cancer 2017 17:850

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  11. Content type: Research article

    The clinical benefit of adjuvant chemotherapy for stage II colorectal cancer (CRC) is controversial. This study aimed to explore novel gene signature to predict outcome benefit of postoperative 5-Fu-based ther...

    Authors: Bangrong Cao, Liping Luo, Lin Feng, Shiqi Ma, Tingqing Chen, Yuan Ren, Xiao Zha, Shujun Cheng, Kaitai Zhang and Changmin Chen

    Citation: BMC Cancer 2017 17:844

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  12. Content type: Research article

    The prevalence of Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is 2 to 5% in the Caucasian population. HNPCC is caused by genomic mutations in DNA mismatch repair genes (MMR), namely MLH1, MSH2, MSH6, PMS2,

    Authors: Jasmine Lee, Yin-Yi Xiao, Yan Yu Sun, Jasminka Balderacchi, Bradley Clark, Jatin Desani, Vivek Kumar, Angela Saverimuthu, Khin Than Win, Yiwu Huang and Yiqing Xu

    Citation: BMC Cancer 2017 17:843

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  13. Content type: Research article

    Evidence suggests that risk of colorectal and prostate cancer is increased among those with a family history of the same disease, particularly among first-degree relatives. However, the aggregation of colorect...

    Authors: Jennifer L. Beebe-Dimmer, Cecilia Yee, Electra Paskett, Ann G. Schwartz, Dorothy Lane, Nynikka R. A. Palmer, Cathryn H. Bock, Rami Nassir and Michael S. Simon

    Citation: BMC Cancer 2017 17:848

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  14. Content type: Research article

    Gastric cancers frequently overexpress the epidermal growth factor receptor (EGFR), which has been implicated in pathological processes including tumor cell motility, invasion and metastasis. Targeting EGFR wi...

    Authors: Simone Keller, Julia Kneissl, Verena Grabher-Meier, Stefan Heindl, Jan Hasenauer, Dieter Maier, Julian Mattes, Peter Winter and Birgit Luber

    Citation: BMC Cancer 2017 17:845

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  15. Content type: Research article

    p53R2 is a target of p53 gene, which is essential for DNA repair, mitochondrial DNA synthesis, protection against oxidative stress, chromosomal instability, chronic inflammation and tumorigenesis. This study i...

    Authors: Jiewei Chen, Shuman Li, Yongbo Xiao, Xuan Zou, Xinke Zhang, Mingshu Zhu, Muyan Cai and Dan Xie

    Citation: BMC Cancer 2017 17:846

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  16. Content type: Study protocol

    In Chile, more than 500 women die every year from cervical cancer, and a majority of Chilean women are not up-to-date with their Papanicolau (Pap) test. Mobile health has great potential in many health areas, ...

    Authors: McKenzie C. Momany, Javiera Martinez-Gutierrez, Mauricio Soto, Daniel Capurro, Francis Ciampi, Beti Thompson and Klaus Puschel

    Citation: BMC Cancer 2017 17:847

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  17. Content type: Research article

    Computational intelligence methods, including non-linear classification algorithms, can be used in medical research and practice as a decision making tool. This study aimed to evaluate the usefulness of artifi...

    Authors: Bogdan Obrzut, Maciej Kusy, Andrzej Semczuk, Marzanna Obrzut and Jacek Kluska

    Citation: BMC Cancer 2017 17:840

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  18. Content type: Research article

    The role of Spalt-like gene-2 (SALL2) in tumorigenesis remains incompletely elucidated. This study investigated the effects of SALL2 on human ovarian carcinoma (OC) A2780 cells and the probable mechanism.

    Authors: Fang Miao, Xueshan Zhang, Yanning Cao, Yue Wang and Xiaoshu Zhang

    Citation: BMC Cancer 2017 17:838

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  19. Content type: Study protocol

    In Japan, S-1 plus cisplatin (SP) regimen has become a standard therapy for patients with advanced gastric cancer. Moreover, the S-1 plus oxaliplatin regimen is now a standard treatment.

    Authors: Yasuyuki Kawamoto, Yoshito Komatsu, Satoshi Yuki, Kentaro Sawada, Tetsuhito Muranaka, Kazuaki Harada, Hiroshi Nakatsumi, Hiraku Fukushima, Atsushi Ishiguro, Masayoshi Dazai, Kazuteru Hatanaka, Michio Nakamura, Ichiro Iwanaga, Minoru Uebayashi, Susumu Sogabe, Yoshimitsu Kobayashi…

    Citation: BMC Cancer 2017 17:837

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