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  1. Content type: Research article

    Next-generation sequencing (NGS) is an efficient and sensitive method to detect mutations from ctDNA. Many features and clinical conditions could significantly affect the concordance between ctDNA and correspo...

    Authors: Nong Yang, Yi Li, Zhidong Liu, Hao Qin, Duanming Du, Xinkai Cao, Xiaoqing Cao, Jun Li, Dongge Li, Bo Jiang, Lincan Duan, Haiyan Yang, Zhenghua Zhang, Hao Lin, Jianying Li, Zhenhua Yang…

    Citation: BMC Cancer 2018 18:319

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  2. Content type: Research article

    The primary objective was to determine human papilloma virus (HPV) clearance rate after cervical biopsy among women with persistent high-risk HPV infection compared with spontaneous HPV clearance rate in the a...

    Authors: K. U. Petry, J. Horn, A. Luyten and R. T. Mikolajczyk

    Citation: BMC Cancer 2018 18:318

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  3. Content type: Research article

    C3H mice have been frequently used in cancer studies as animal models of spontaneous liver tumors and chemically induced hepatocellular carcinoma (HCC). Epigenetic modifications, including DNA methylation, are...

    Authors: Junya Matsushita, Kazuyuki Okamura, Kazuhiko Nakabayashi, Takehiro Suzuki, Yu Horibe, Tomoko Kawai, Toshihiro Sakurai, Satoshi Yamashita, Yoshikazu Higami, Gaku Ichihara, Kenichiro Hata and Keiko Nohara

    Citation: BMC Cancer 2018 18:317

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  4. Content type: Research article

    It is unclear whether germline breast cancer susceptibility gene mutations affect breast cancer related outcomes. We wanted to evaluate mutation patterns in 20 breast cancer susceptibility genes and correlate ...

    Authors: Yong Alison Wang, Jhih-Wei Jian, Chen-Fang Hung, Hung-Pin Peng, Chi-Fan Yang, Hung-Chun Skye Cheng and An-Suei Yang

    Citation: BMC Cancer 2018 18:315

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  5. Content type: Research article

    Age is an important prognostic factor in papillary thyroid cancer (PTC), with better survival observed in patients < 45 years of age, regardless of stage. Although the impact of increasing age on PTC-related s...

    Authors: Rondi M. Kauffmann, J. Blair Hamner, Philip H. G. Ituarte and John H. Yim

    Citation: BMC Cancer 2018 18:316

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  6. Content type: Research article

    Typically, women in South Africa (SA) are diagnosed with breast cancer when they self-present with symptoms to health facilities. The aim of this study was to determine the pathway that women follow to breast ...

    Authors: Jennifer Moodley, Lydia Cairncross, Thurandrie Naiker and Deborah Constant

    Citation: BMC Cancer 2018 18:312

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  7. Content type: Research article

    Recent studies have reported TIMs play an important role in tumors progression or regression, but the effect of TIMs in biliary tract cancer remains unclear. The aim of this study is to investigate the prognos...

    Authors: Xiaobo Bo, Jie Wang, Tao Suo, Xiaoling Ni, Han Liu, Sheng Shen, Min Li, Yueqi Wang, Houbao Liu and Jiejie Xu

    Citation: BMC Cancer 2018 18:313

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  8. Content type: Case report

    We report the successful treatment of the patient with osimertinib 80 mg/day following disease progression and a discordance in the detection of a mechanism of resistance epithelial growth factor receptor (EGF...

    Authors: Isa Mambetsariev, Lalit Vora, Kim Wai Yu and Ravi Salgia

    Citation: BMC Cancer 2018 18:314

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  9. Content type: Review article

    Despite the remarkable advances in the early diagnosis and treatment, overall 5-year survival rate of patients with pancreatic cancer is less than 10%. Gemcitabine (GEM), a cytidine nucleoside analogue and rib...

    Authors: Toshinori Ozaki, Meng Yu, Danjing Yin, Dan Sun, Yuyan Zhu, Youquan Bu and Meixiang Sang

    Citation: BMC Cancer 2018 18:309

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  10. Content type: Research article

    Prediction of the outcome of sorafenib therapy using biomarkers is an unmet clinical need in patients with advanced hepatocellular carcinoma (HCC). The aim was to develop and validate a biomarker-based model f...

    Authors: Hwi Young Kim, Dong Hyeon Lee, Jeong-Hoon Lee, Young Youn Cho, Eun Ju Cho, Su Jong Yu, Yoon Jun Kim and Jung-Hwan Yoon

    Citation: BMC Cancer 2018 18:307

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  11. Content type: Research article

    The expression of circular RNA (circRNA) may affect tumor progression. However, there have been no systemic meta-analysis for cancer diagnosis by using circRNAs in clinical till now. Herein, we aimed to collec...

    Authors: Miao Wang, Yuxi Yang, Jian Xu, Wen Bai, Xueli Ren and Huijian Wu

    Citation: BMC Cancer 2018 18:303

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  12. Content type: Research article

    The VeriStrat test is a serum proteomic signature originally discovered in non-responders to second line gefitinib treatment and subsequently used to predict differential benefit from erlotinib versus chemothe...

    Authors: Mary Jo Fidler, Cristina L. Fhied, Joanna Roder, Sanjib Basu, Selina Sayidine, Ibtihaj Fughhi, Mark Pool, Marta Batus, Philip Bonomi and Jeffrey A. Borgia

    Citation: BMC Cancer 2018 18:310

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  13. Content type: Research article

    Tumor testing for mutations in the epidermal growth factor receptor (EGFR) gene is indicated for all newly diagnosed, metastatic lung cancer patients, who may be candidates for first-line treatment with an EGFR t...

    Authors: Julie A. Lynch, Brygida Berse, Merry Rabb, Paul Mosquin, Rob Chew, Suzanne L. West, Nicole Coomer, Daniel Becker and John Kautter

    Citation: BMC Cancer 2018 18:306

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  14. Content type: Case report

    Everolimus was recently approved for the treatment of neuroendocrine tumors. However, its efficacy and tolerability in hemodialysis patients with end-stage renal disease is not established.

    Authors: M. P. Brizzi, A. La Salvia, M. Tampellini, C. Sonetto, M. Volante and G. V. Scagliotti

    Citation: BMC Cancer 2018 18:311

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  15. Content type: Research article

    Liposarcomas are the second most common type of soft tissue sarcomas, 30–50% of these are of myxoid subtype. The aim of this retrospective study was to analyze the local control rate, the metastatic pattern an...

    Authors: Hans Roland Dürr, Jessica Rauh, Andrea Baur-Melnyk, Thomas Knösel, Lars Lindner, Falk Roeder, Volkmar Jansson and Alexander Klein

    Citation: BMC Cancer 2018 18:304

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  16. Content type: Case report

    Acantholytic squamous cell carcinoma (ASQCC), histologically characterized by intercellular bridge loosening, is recognized as a rare variant of squamous cell carcinoma (SQCC). ASQCC may demonstrate a worse pr...

    Authors: Kenji Yorita, Kazuya Tsuji, Yoko Takano, Naoto Kuroda, Kei Sakamoto, Kaoru Arii, Yukio Yoshimoto, Kimiko Nakatani and Satoshi Ito

    Citation: BMC Cancer 2018 18:300

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  17. Content type: Case report

    Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal tract and liver and peritoneum are the main sites of recurrence. Ovarian metastases from GIST are very rare.

    Authors: Antonio De Leo, Margherita Nannini, Giulia Dondi, Donatella Santini, Milena Urbini, Elisa Gruppioni, Pierandrea De Iaco, Anna Myriam Perrone and Maria Abbondanza Pantaleo

    Citation: BMC Cancer 2018 18:301

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  18. Content type: Research article

    The WHO recognises that community pharmacists are the most accessible healthcare professionals to the general public. Most patients regularly visit community pharmacies for health information and also seek adv...

    Authors: Kofi Boamah Mensah, Frasia Oosthuizen and Adwoa Bemah Bonsu

    Citation: BMC Cancer 2018 18:299

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  19. Content type: Research article

    Cervical cancer is one of the most easily preventable forms of female cancers if early screening and diagnosis is made. Low awareness level about the disease and risk factors, beliefs about the disease, poor a...

    Authors: Yitagesu Habtu, Samuel Yohannes and Tariku Laelago

    Citation: BMC Cancer 2018 18:298

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  20. Content type: Research article

    Thyroid cancer is the most common malignant disease of the endocrine system. Previous studies indicate a rapid increase in the incidence of thyroid cancer in recent decades, and this increase has aroused the g...

    Authors: Lingbin Du, Youqing Wang, Xiaohui Sun, Huizhang Li, Xinwei Geng, Minghua Ge and Yimin Zhu

    Citation: BMC Cancer 2018 18:291

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  21. Content type: Research article

    Trastuzumab (Herceptin® [H]) is the standard of care for HER2-positive locally advanced/metastatic breast cancer and gastric/gastroesophageal junction (GEJ) cancer. However, there is a paucity of data availabl...

    Authors: Volkmar Müller, Michael Clemens, Jacek Jassem, Nedal Al-Sakaff, Petra Auclair, Eveline Nüesch, Debbie Holloway, Mona Shing and Yung-Jue Bang

    Citation: BMC Cancer 2018 18:295

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