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  1. For patients with locally advanced rectal cancer (LARC), total neoadjuvant therapy (TNT), namely, intensifying preoperative treatment through the integration of radiotherapy and systemic chemotherapy before su...

    Authors: Tongzhen Xu, Lingling Feng, Wenjue Zhang, Haoyue Li, Huiying Ma, Muyasha Abulimiti, Yutong Tan, Feiyan Deng, Wenting Huang, Shuangmei Zou, Wenyan Kang, Liming Jiang, Ying Wang, Chen Hu, Yinggang Chen, Haitao Zhou…
    Citation: BMC Cancer 2024 24:501
    Content type: Study Protocol Published on:

  2. Our aim was to develop a validated Patient Reported Experience Measure (PREM) to capture patient and carer experience during participation in experimental cancer medicine trials (ECM): called PREM-ECM.

    Authors: Chelsea S. Sawyer, Sally Taylor, Louise Carter, Melissa Stanworth, Michelle Davies, Fiona Thistlethwaite, Jo Taylor, Charlotte Eastwood and Janelle Yorke
    Citation: BMC Cancer 2024 24:500
    Content type: Research Published on:

  3. Germline mutations in BRCA1 and BRCA2 genes are among the main causes of hereditary ovarian cancer. Identifying these mutations may reduce cancer risk, facilitate early detection, and enable personalized treat...

    Authors: Caroline de Oliveira Ferreira, Vandré Cabral Gomes Carneiro and Carolline Araujo Mariz
    Citation: BMC Cancer 2024 24:499
    Content type: Research Published on:

  4. Lack of agreed terminology and definitions in healthcare compromises communication, patient safety, optimal management of adverse events, and research progress. The purpose of this scoping review was to unders...

    Authors: Kerrie Curtis, Karla Gough, Meinir Krishnasamy, Elena Tarasenko, Geoff Hill and Samantha Keogh
    Citation: BMC Cancer 2024 24:498
    Content type: Research Published on:

  6. Ferroptosis has important value in cancer treatment. It is significant to explore the new ferroptosis-related lncRNAs prediction model in Hepatocellular carcinoma (HCC) and the potential molecular mechanism of...

    Authors: Ke Zong, Caifeng Lin, Kai Luo, Yilei Deng, Hongfei Wang, Jianfei Hu, Shi Chen and Renfeng Li
    Citation: BMC Cancer 2024 24:496
    Content type: Research Published on:

  7. Although many studies have explored the correlation between quality of life and survival, none have reported this relationship for specific cancers assessed at distinct time points. This meta-analysis aimed to...

    Authors: Taro Okayama, Katsuyoshi Suzuki, Shinichiro Morishita, Junichiro Inoue, Takashi Tanaka, Jiro Nakano and Takuya Fukushima
    Citation: BMC Cancer 2024 24:495
    Content type: Systematic Review Published on:

  8. Informal caregivers (ICs) of patients with cancer provide essential and mainly uncompensated care. A self-perceived preparedness to care for the patient is associated with a lower caregiver burden, described a...

    Authors: Birgitta Johansson, Åsa Cajander, Awais Ahmad, Emma Ohlsson-Nevo, Per Fransson, Brith Granström, Louise von Essen, Ulrica Langegård, Mona Pettersson, Anna Henriksson and Ylva Tiblom Ehrsson
    Citation: BMC Cancer 2024 24:494
    Content type: Study Protocol Published on:

  9. Muscle mass is important for metastatic prostate cancer survival and quality of life (QoL). The backbone of treatment for men with metastatic castration sensitive prostate cancer (mCSPC) is androgen deprivatio...

    Authors: Adriana M Coletta, Lea Haverbeck Simon, Kelsey Maslana, Sarah Taylor, Kish Larson, Pamela A Hansen, Vinay Mathew Thomas, Cornelia M Ulrich, Manish Kohli, Jonathan Chipman, Umang Swami, Sumati Gupta, Benjamin L Maughan and Neeraj Agarwal
    Citation: BMC Cancer 2024 24:493
    Content type: Study Protocol Published on:

  11. This study aimed to systematically analyze the effect of a serine/threonine kinase (STK11) mutation (STK11mut) on therapeutic efficacy and prognosis in patients with non-small cell lung cancer (NSCLC).

    Authors: Ke Xu, Weinan Lu, Airu Yu, Hongwei Wu and Jie He
    Citation: BMC Cancer 2024 24:491
    Content type: Research Published on:

  12. Patients with rheumatologic preexisting autoimmune disease (PAD) have not been enrolled in clinical trials of immune checkpoint inhibitors (ICIs). Therefore, the risks and benefits of ICI therapy in such patie...

    Authors: Xin Liu, Su Li, Liyuan Ke and Hongxia Cui
    Citation: BMC Cancer 2024 24:490
    Content type: Systematic Review Published on:

  13. Next-generation sequencing (NGS) is essential for lung cancer treatment. It is important to collect sufficient tissue specimens, but sometimes we cannot obtain large enough samples for NGS analysis. We investi...

    Authors: Chihiro Mimura, Rei Takamiya, Shodai Fujimoto, Takafumi Fukui, Atsuhiko Yatani, Jun Yamada, Mizuki Takayasu, Naoya Takata, Hiroki Sato, Kiyoko Fukuda, Koichi Furukawa, Daisuke Hazama, Naoko Katsurada, Masatsugu Yamamoto, Shingo Matsumoto, Koichi Goto…
    Citation: BMC Cancer 2024 24:489
    Content type: Research Published on:

  14. Meningiomas are among the most common primary tumors of the central nervous system. Previous research into the meningioma histological appearance, genetic markers, transcriptome and epigenetic landscape has re...

    Authors: D. Orešković, A. Madero Pohlen, I. Cvitković, J.F. Alen, M. Raguž, A. Álvarez-Sala de la Cuadra, G.J. Bazarra Castro, Z. Bušić, I. Konstantinović, V. Ledenko, C. Martínez Macho, D. Müller, M. Žarak, N. Jovanov-Milosevic, D. Chudy and T. Marinović
    Citation: BMC Cancer 2024 24:488
    Content type: Research Published on:

  15. Authors: Alessio Cirillo, Daniele Marinelli, Umberto Romeo, Daniela Messineo, Francesca De Felice, Marco De Vincentiis, Valentino Valentini, Silvia Mezi, Filippo Valentini, Luca Vivona, Antonella Chiavassa, Bruna Cerbelli, Daniele Santini, Paolo Bossi, Antonella Polimeni, Paolo Marchetti…
    Citation: BMC Cancer 2024 24:487
    Content type: Correction Published on:

    The original article was published in BMC Cancer 2024 24:430

  16. The antiviral drug Nirmatrelvir was found to be a key drug in controlling the progression of pneumonia during the infectious phase of COVID-19. However, there are very few options for effective treatment for c...

    Authors: Xiaoyan Yin, Wanqi Zhu, Xiaoyong Tang, Guangjian Yang, Xianguang Zhao, Kaikai Zhao, Liyang Jiang, Xiaolin Li, Hong Zhao, Xin Wang, Yuanyuan Yan, Ligang Xing, Jinming Yu, Xiangjiao Meng and Hanxi Zhao
    Citation: BMC Cancer 2024 24:486
    Content type: Research Published on:

  17. Patients-derived xenograft (PDX) model have been widely used for tumor biological and pathological studies. However, the metabolic similarity of PDX tumor to the primary cancer (PC) is still unknown.

    Authors: Shi Wen, Xianchao Lin, Wei Luo, Yu Pan, Fei Liao, Zhenzhao Wang, Bohan Zhan, Jianghua Feng and Heguang Huang
    Citation: BMC Cancer 2024 24:485
    Content type: Research Published on:

  18. This article examines the potential of using liquid biopsy with piRNAs to study cancer survival outcomes. While previous studies have explored the relationship between piRNA expression and cancer patient outco...

    Authors: Mohammad Taghizadeh, Tohid Jafari-Koshki, Vahid Jafarlou, Mortaza Raeisi, Leila Alizadeh, Yousef Roosta, Somaieh Matin, Rahele Jabari, Daniel Sur and Abbas Karimi
    Citation: BMC Cancer 2024 24:484
    Content type: Systematic Review Published on:

  19. To compare the clinical characteristics and prognoses of patients with isolated regional lymph node recurrent nasopharyngeal carcinoma (irrNPC) who underwent surgery or re-irradiation treatment.

    Authors: Yuebing Chen, Yiping Huang, Xiaoqiang Chen, Zhiwei Chen, Xiane Peng, Shaojun Lin, Cheng Lin and Jingfeng Zong
    Citation: BMC Cancer 2024 24:483
    Content type: Research Published on:

  20. Therapies for metastatic castration-resistant prostate cancer (mCRPC) include targeting the androgen receptor (AR) with androgen receptor inhibitors (ARIs) and prostate-specific membrane antigen (PSMA). Having...

    Authors: Haiyan E. Liu, Meghah Vuppalapaty, Christian R. Hoerner, Colin P. Bergstrom, Michael Chiu, Clementine Lemaire, James Che, Amanpreet Kaur, Adam Dimmick, Sean Liu, Thomas J. Metzner, Menna Araya, Steve Crouse, Markus Sprenger-Haussels, Martin Schlumpberger, John T. Leppert…
    Citation: BMC Cancer 2024 24:482
    Content type: Research Published on:

  21. The treatment for lung oligometastasis from colorectal cancer (CRC) remains challenging. This retrospective study aimed to compare the local tumor control, survival and procedure-related complications in CRC p...

    Authors: Yuliang Li, Zitong Chen, Shuhui Tian, Xujian Han, Changjun Wang, Yongzheng Wang and Bin Liu
    Citation: BMC Cancer 2024 24:481
    Content type: Research Published on:

  22. The treatment of hepatocellular carcinoma (HCC) patients exhibiting high-risk characteristics (Vp4, and/or bile duct invasion, and/or tumor occupancy ≥ 50%) lacks standardized approaches and yields unfavorable...

    Authors: Xu Chang, Xinge Li, Peng Sun, Zhenfeng Li, Pengfei Sun and Shangkun Ning
    Citation: BMC Cancer 2024 24:480
    Content type: Research Published on:

  23. Rectal cancer treatment has transformed in recent years, with neoadjuvant treatment (NT) and total neoadjuvant treatment (TNT) aiming to enhance pathological responses. This pioneering study in our country del...

    Authors: Misbah Younus Soomro, Saqib Raza Khan, Hafiz Muhammad, Sujjawal Ahmad, Nawazish Zehra, Insia Ali, Mirza Rameez Samar, Arif Hameed, Munira Moosajee and Yasmin Abdul Rashid
    Citation: BMC Cancer 2024 24:479
    Content type: Research Published on:

  24. Pancreatic cancer is the foremost contributor to cancer-related deaths globally, and its prevalence continues to rise annually. Nevertheless, the underlying mechanisms behind its development remain unclear and...

    Authors: Feng Zhao, Anli Chen, Xiaotian Wu, Xiangyu Deng, Jiali Yang and Jianjiang Xue
    Citation: BMC Cancer 2024 24:478
    Content type: Research Published on:

  25. Limited evidence exists on the population attributable fraction (PAF) of cancer cases and deaths in Latin America. In Peru several studies have been published regarding the PAF of various risk factors and thei...

    Authors: Jhony A. De La Cruz-Vargas, Willy Ramos, Willer Chanduví, Lucy E. Correa-López, Nadia Guerrero, Joan Loayza-Castro, Irene Tami-Maury and Diego Venegas
    Citation: BMC Cancer 2024 24:477
    Content type: Research Published on:

  26. Anxiety is a prevalent comorbidity in lung cancer (LC) patients associated with a decline in quality of life. Dehydroepiandrosterone (DHEA), a neuroactive steroid, levels rise in response to stress. Prior rese...

    Authors: Jia-Rong Wu, Vincent Chin -Hung Chen, Yu-Hung Fang, Ching-Chuan Hsieh and Shu-I Wu
    Citation: BMC Cancer 2024 24:476
    Content type: Research Published on:

  27. Underlying liver disease is correlated with hepatocellular carcinoma (HCC) development in patients with hepatitis B virus (HBV) infection. However, the impact of hepatic inflammation and fibrosis on the patien...

    Authors: Xiangyong Hao, Liangliang Xu, Xiang Lan, Bo Li and Hui Cai
    Citation: BMC Cancer 2024 24:475
    Content type: Research Published on:

  28. In recent years, there has been extensive research on the role of exercise as an adjunctive therapy for cancer. However, the potential mechanisms underlying the anti-tumor therapy of exercise in lung cancer re...

    Authors: Sai-Nan Miao, Meng-Qi Chai, Xiang-Yu Liu, Cheng-Yu Wei, Cun-Cun Zhang, Ning-Ning Sun, Qing-Ze Fei, Lin-Lin Peng and Huan Qiu
    Citation: BMC Cancer 2024 24:474
    Content type: Research Published on:

  30. Prostate cancer (PCa) is becoming the most common malignancy in men worldwide. We investigated the effect of astragaloside IV combined with PESV on the gut microbiota and metabolite of PCa mice and the process...

    Authors: Xujun You, Junfeng Qiu, Qixin Li, Qing Zhang, Wen Sheng, Yiguo Cao and Wei Fu
    Citation: BMC Cancer 2024 24:472
    Content type: Research Published on:

  34. To assess the diagnostic performance of a panel of standard tumor markers (TMs) in patients hospitalized with significant involuntary weight loss (IWL) and elevated levels of inflammation biomarkers, and a com...

    Authors: Morgane Gronnier, Kaies Hedhli, Chloé Sauzay, Valéry Salle, Pierre Duhaut, Jean Schmidt and Amandine Dernoncourt
    Citation: BMC Cancer 2024 24:468
    Content type: Research Published on:

  35. The incidence of thyroid cancer as the most common type of endocrine gland malignancy has risen more significantly than any malignancies in recent years. Estimated new cases of thyroid cancer in the United Sta...

    Authors: Zahra Maleki, Jafar Hassanzadeh and Haleh Ghaem
    Citation: BMC Cancer 2024 24:467
    Content type: Research Published on:

  36. [18 F]-Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) has the ability to detect local and/or regional recurrence as well as distant metastasis. We aimed to evaluate the prog...

    Authors: Zhe Dong, Gao-Yuan Wang, Dong-Yu Dai, Guan-Jie Qin, Ling-Long Tang, Cheng Xu and Jun Ma
    Citation: BMC Cancer 2024 24:466
    Content type: Research Published on:

  37. Gastric cancer (GC) lacks serum biomarkers with clinical diagnostic value. Multi-omics analysis is an important approach to discovering cancer biomarkers. This study aimed to identify and validate serum biomar...

    Authors: Shao-Song Liu, Qin-Si Wan, Cong Lv, Jin-Ke Wang, Song Jiang, Dan Cai, Mao-Sheng Liu, Ting Wang and Kun-He Zhang
    Citation: BMC Cancer 2024 24:465
    Content type: Research Published on:

  38. In this study, we retrospectively investigated the prognostic role of pre-treatment neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in esophageal squamous cell carcinoma patients (E...

    Authors: Qirong Man, Peishun Li, Jing Fan, Sen Yang, Chao Xing, Yunling Bai, Miaomiao Hu, Baohu wang and Kaixian Zhang
    Citation: BMC Cancer 2024 24:464
    Content type: Research Published on:

  39. Clear cell renal cell carcinoma (ccRCC) is associated with a high prevalence of cancer-related deaths. The survival rates of patients are significantly lower in late-stage ccRCC than in early-stage ccRCC, due ...

    Authors: Jun Wang, Xiaoming He, Yuanyuan Mi, Yong Q. Chen, Jie Li and Rong Wang
    Citation: BMC Cancer 2024 24:463
    Content type: Research Published on:

  41. Despite numerous studies on racial/ethnic disparities among patients with breast cancer, there is a paucity of literature evaluating racial/ethnic differences in 21-gene recurrence score (RS) and survival diff...

    Authors: Jasmin Gill, Keerti Yendamuri, Udit Chatterjee, Song Yao, Oluwadamilola T. Oladeru, Anurag K. Singh and Sung Jun Ma
    Citation: BMC Cancer 2024 24:461
    Content type: Research Published on:

  42. To predict pathological complete response (pCR) in patients receiving neoadjuvant immunochemotherapy (nICT) for esophageal squamous cell carcinoma (ESCC), we explored the factors that influence pCR after nICT ...

    Authors: Yu Yang, Yan Yi, Zhongtang Wang, Shanshan Li, Bin Zhang, Zheng Sang, Lili Zhang, Qiang Cao and Baosheng Li
    Citation: BMC Cancer 2024 24:460
    Content type: Research Published on:

  43. Head and neck squamous cell carcinoma (HNSCC) represents a common and heterogeneous malignancy of the oral cavity, pharynx and larynx. Surgery and radio(chemo)therapy are the standard treatment options and als...

    Authors: Christian Idel, Jonas Fleckner, Kirstin Plötze-Martin, Lotte Werner, Dirk Rades, Marie-Nicole Theodoraki, Linda Hofmann, Diana Huber, Anke Leichtle, Thomas K. Hoffmann, Karl-Ludwig Bruchhage and Ralph Pries
    Citation: BMC Cancer 2024 24:459
    Content type: Research Published on:

  44. The identification of survival predictors is crucial for early intervention to improve outcome in acute myeloid leukemia (AML). This study aim to identify chest computed tomography (CT)-derived features to pre...

    Authors: Xiaoping Yi, Huien Zhan, Jun Lyu, Juan Du, Min Dai, Min Zhao, Yu Zhang, Cheng Zhou, Xin Xu, Yi Fan, Lin Li, Baoxia Dong, Xinya Jiang, Zeyu Xiao, Jihao Zhou, Minyi Zhao…
    Citation: BMC Cancer 2024 24:458
    Content type: Research Published on:

  45. The SARS-CoV-2 (COVID-19) pandemic has strained healthcare systems and presented unique challenges for children requiring cancer care, particularly in low- and middle-income countries. This study aimed to asse...

    Authors: Yotham Gwanika, Hannah E. Rice, Madeline Metcalf, Pamela Espinoza, Happiness D. Kajoka, Henry E. Rice, Catherine Staton, Blandina T. Mmbaga, Esther Majaliwa, Emily R. Smith and Cesia Cotache-Condor
    Citation: BMC Cancer 2024 24:457
    Content type: Research Published on:

  46. The incidence of early-onset colorectal cancer (EOCRC), diagnosed before age 50, has been rising in many countries in the past few decades. This study aims to evaluate this trend in Aotearoa New Zealand and as...

    Authors: Oliver Waddell, John Pearson, Andrew McCombie, Harriet Marshall, Rachel Purcell, Jacqueline Keenan, Tamara Glyn and Frank Frizelle
    Citation: BMC Cancer 2024 24:456
    Content type: Research Published on:

  48. Evidence from observational studies suggests an association between chronic obstructive pulmonary disease (COPD) and lung cancer. The potential interactions between the immune system and the lungs may play a c...

    Authors: Dengfeng Zhang, Haitao Liu, Fangchao Zhao, Pengfei Guo, Jing Li, Tianxing Lu, Zhirong Li and Shujun Li
    Citation: BMC Cancer 2024 24:453
    Content type: Research Published on:

  49. While surgical resection remains the primary treatment approach for symptomatic or growing meningiomas, radiotherapy represents an auspicious alternative in patients with meningiomas not safely amenable to sur...

    Authors: Maximilian Y. Deng, Amanda Salviano da Silva, Pauline Carlotta Göller, Laila König, Henning Schäfer, Cecile Maire, Adriane Lentz-Hommertgen, Thomas Held, Sebastian Regnery, Tanja Eichkorn, Florian Stritzke, Lukas Bauer, Daniel Schnell, Klaus Herfarth, Andreas von Deimling, Sandro Krieg…
    Citation: BMC Cancer 2024 24:449
    Content type: Study Protocol Published on:

  50. High rates of negative intrusive thoughts have been reported among cancer patients. Prevalent users of beta-blocker therapy have reported lower levels of cancer related intrusive thoughts than non-user. The ai...

    Authors: Carolina Ehrencrona, Ying Li, Eva Angenete, Eva Haglind, Stefan Franzén, Anna Grimby-Ekman and David Bock
    Citation: BMC Cancer 2024 24:447
    Content type: Research Published on:

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