Endothelial Dll4 overexpression reduces vascular response and inhibits tumor growth and metastasization in vivo
The inhibition of Delta-like 4 (Dll4)/Notch signaling has been shown to result in excessive, nonfunctional vessel proliferation and significant tumor growth suppression. However, safety concerns emerged with t...
BMC Cancer 2017 17:189
Published on: 14 March 2017