Surgical oncology, cancer imaging, and interventional therapeutics

Section edited by Stephen P. Povoski

This section focuses on clinical research that impacts on the diagnosis and treatment of cancer using surgery, diagnostic imaging, interventional therapeutics, and surgical pathology.

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  1. Research article

    The safety and efficacy of percutaneous intraductal radiofrequency ablation in unresectable malignant biliary obstruction: A single-institution experience

    Patients with unresectable malignant biliary obstruction have limited life expectancy because of limited stent patency and tumor progression. The aim of our study was to retrospectively evaluate the safety and...

    Wei Cui, Wenzhe Fan, Mingjian Lu, Yingqiang Zhang, Wang Yao, Jiaping Li and Yu Wang

    BMC Cancer 2017 17:288

    Published on: 24 April 2017

  2. Research article

    Is adjuvant chemotherapy necessary in pT1N1 gastric cancer?

    Due to a lack of consensus on adjuvant treatments for pT1N1 gastric cancer, surgeons face a dilemma when deciding treatments for patients with pT1N1 gastric cancer after gastrectomy. The objective of this stud...

    Hyun Beak Shin, Ji Yeong An, Seung Hyoung Lee, Yoon Young Choi, Jong Won Kim, Soo Sang Sohn and Sung Hoon Noh

    BMC Cancer 2017 17:287

    Published on: 22 April 2017

  3. Study protocol

    Contrast-enhanced US with Perfluorobutane(Sonazoid) used as a surveillance test for Hepatocellular Carcinoma (HCC) in Cirrhosis (SCAN): an exploratory cross-sectional study for a diagnostic trial

    Ultrasonography (US) is widely used as a standard surveillance tool for patients who are at a high risk of having hepatocellular carcinoma (HCC); however, conventional B-mode US appears to be insufficient in o...

    Ji Hoon Park, Mi-Suk Park, So Jung Lee, Woo Kyoung Jeong, Jae Young Lee, Min Jung Park, Kyunghwa Han, Chung Mo Nam, Seong Ho Park and Kyoung Ho Lee

    BMC Cancer 2017 17:279

    Published on: 18 April 2017

  4. Research article

    Appraising the holistic value of Lenvatinib for radio-iodine refractory differentiated thyroid cancer: A multi-country study applying pragmatic MCDA

    The objective of the study was to reveal through pragmatic MCDA (EVIDEM) the contribution of a broad range of criteria to the value of the orphan drug lenvatinib for radioiodine refractory differentiated thyro...

    Monika Wagner, Hanane Khoury, Liga Bennetts, Patrizia Berto, Jenifer Ehreth, Xavier Badia and Mireille Goetghebeur

    BMC Cancer 2017 17:272

    Published on: 17 April 2017

  5. Research article

    A prediction model for lymph node metastases using pathologic features in patients intraoperatively diagnosed as stage I non-small cell lung cancer

    There is little information on which pattern should be chosen to perform lymph node dissection for stage I non-small-cell lung cancer. This study aimed to develop a model for predicting lymph node metastasis u...

    Fei Zhao, Yue Zhou, Peng-Fei Ge, Chen-Jun Huang, Yue Yu, Jun Li, Yun-Gang Sun, Yang-Chun Meng, Jian-Xia Xu, Ting Jiang, Zhi-Xuan Zhang, Jin-Peng Sun and Wei Wang

    BMC Cancer 2017 17:267

    Published on: 13 April 2017

  6. Study protocol

    Gamma probe and ultrasound guided fine needle aspiration cytology of the sentinel node (GULF) trial - overview of the literature, pilot and study protocol

    Sentinel node (SN) biopsy (SNB) detects clinically occult metastases of breast cancer and melanoma in 20–30%. Wound infections, seroma and lymph edema occur in up to 10%. Targeted ultrasound (US) of the SN, (w...

    Charlotte M.C. Oude Ophuis, Lisa (Linetta) B. Koppert, Cécile de Monyé, Carolien H.M. van Deurzen, Senada Koljenović, Alexander C.J. van Akkooi, Cornelis (Kees) Verhoef and Dirk J. Grünhagen

    BMC Cancer 2017 17:258

    Published on: 12 April 2017

  7. Study protocol

    A multicentre randomised controlled trial to evaluate the efficacy, morbidity and functional outcome of endoscopic transanal proctectomy versus laparoscopic proctectomy for low-lying rectal cancer (ETAP-GRECCAR 11 TRIAL): rationale and design

    Total mesorectal excision is the standard surgical treatment for mid- and low-rectal cancer. Laparoscopy represents a clear leap forward in the management of rectal cancer patients, offering significant improv...

    Bernard Lelong, Cécile de Chaisemartin, Helene Meillat, Sandra Cournier, Jean Marie Boher, Dominique Genre, Mehdi Karoui, Jean Jacques Tuech and Jean Robert Delpero

    BMC Cancer 2017 17:253

    Published on: 11 April 2017

  8. Research article

    Metastatic polyp of the gallbladder from renal cell carcinoma

    Gallbladder metastasis from renal cell carcinoma (RCC) is extremely rare. The purpose of this study is to clarify the characteristics of metastatic RCC to gallbladder.

    Bor-Uei Shyr, Shih-Chin Chen, Yi-Ming Shyr, Rheun-Chuan Lee and Shin-E Wang

    BMC Cancer 2017 17:244

    Published on: 4 April 2017

  9. Research article

    The IGCA staging system is more accurate than AJCC7 system in stratifying survival of patients with gastric cancer in stage III

    A new staging system recently proposed by the IGCA has demonstrated a better capacity of stratifying different prognoses for gastric cancer than the 7th edition AJCC staging system (AJCC7). The aim of this stu...

    Ping Shu, Jing Qin, Kuntang Shen, Weidong Chen, Fenglin Liu, Yong Fang, Xuefei Wang, Hongshan Wang, Zhenbin Shen, Yihong Sun and Xinyu Qin

    BMC Cancer 2017 17:238

    Published on: 31 March 2017

  10. Research article

    Clinical impact of postoperative loss in psoas major muscle and nutrition index after radical cystectomy for patients with urothelial carcinoma of the bladder

    Although the significance of preoperative nutritional status has been investigated, there is no report regarding the relationship of their postoperative changes on outcomes in patients who underwent radical cy...

    Makito Miyake, Yosuke Morizawa, Shunta Hori, Nagaaki Marugami, Keiji Shimada, Daisuke Gotoh, Yoshihiro Tatsumi, Yasushi Nakai, Takeshi Inoue, Satoshi Anai, Kazumasa Torimoto, Katsuya Aoki, Nobumichi Tanaka and Kiyohide Fujimoto

    BMC Cancer 2017 17:237

    Published on: 31 March 2017

  11. Case report

    Follicular thyroid carcinoma metastasis to the facial skeleton: a systematic review

    Follicular thyroid carcinoma (FTC) metastasis to the facial skeleton is exceedingly rare. A case of FTC metastasizing to the mandible is presented and a systematic review of the literature describing thyroid m...

    Varun V. Varadarajan, Elizabeth K. Pace, Vatsal Patel, Raja Sawhney, Robert J. Amdur and Peter T. Dziegielewski

    BMC Cancer 2017 17:225

    Published on: 28 March 2017

  12. Research article

    ABCG2 is a potential prognostic marker of overall survival in patients with clear cell renal cell carcinoma

    ATP-binding cassette sub-family G member 2 (ABCG2) is a semi-transport protein that plays a major role in multidrug resistance. We aimed to evaluate the prognostic significance of ABCG2 expression in patients wit...

    Haofei Wang, Fangxiu Luo, Zhe Zhu, Zhaoping Xu, Xin Huang, Renyi Ma, Hongchao He, Yu Zhu, Kun Shao and Juping Zhao

    BMC Cancer 2017 17:222

    Published on: 27 March 2017

  13. Research article

    Morphological and phenotypical features of ovarian metastases in breast cancer patients

    Autotransplantation of frozen-thawed ovarian tissue is a method to preserve ovarian function and fertility in patients undergoing gonadotoxic therapy. In oncology patients, the safety cannot yet be guaranteed,...

    Inge T. A. Peters, Merle A. van der Steen, Bertine W. Huisman, Carina G. J .M. Hilders, Vincent T. H. B. M. Smit, Alexander L. Vahrmeijer, Cornelis F. M. Sier, J. Baptist Trimbos and Peter J. K. Kuppen

    BMC Cancer 2017 17:206

    Published on: 21 March 2017

  14. Research article

    Early evaluation of sunitinib for the treatment of advanced gastroenteropancreatic neuroendocrine neoplasms via CT imaging: RECIST 1.1 or Choi Criteria?

    The aim of this study was to assess and compare the Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1) and the Choi criteria in evaluating the early response of advanced gastroenteropancreat...

    Yanji Luo, Jie Chen, Kun Huang, Yuan Lin, Minhu Chen, Ling Xu, Zi-Ping Li and Shi-Ting Feng

    BMC Cancer 2017 17:154

    Published on: 23 February 2017

  15. Research article

    Low CCL17 expression associates with unfavorable postoperative prognosis of patients with clear cell renal cell carcinoma

    Chemokine (C–C motif) ligand 17 (CCL17) is a chemokine mainly produced by myeloid dendritic cells. It is a ligand for CC chemokine receptor 4 (CCR4) and CC chemokine receptor 8 (CCR8). The aim of this study wa...

    Ying Xiong, Li Liu, Yu Xia, Jiajun Wang, Wei Xi, Qi Bai, Yang Qu, Jiejie Xu and Jianming Guo

    BMC Cancer 2017 17:117

    Published on: 8 February 2017

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