Medical and radiation oncology

Section edited by Dirk Vordermark

This section focuses on clinical research that impacts on the treatment of cancer using systemic chemotherapy, targeted therapy, and radiation.

Previous Page Page 1 of 15 Next Page
  1. Research article

    Distinct immunophenotypes and prognostic factors in renal cell carcinoma with sarcomatoid differentiation: a systematic study of 19 immunohistochemical markers in 42 cases

    Renal cell carcinoma (RCC) with sarcomatoid differentiation is a relatively rare tumor containing both carcinoma and sarcomatoid components. However, there has not been a systemic study on immunophenotypes of ...

    Wenjuan Yu, Yuewei Wang, Yanxia Jiang, Wei Zhang and Yujun Li

    BMC Cancer 2017 17:293

    Published on: 27 April 2017

  2. Research article

    Transcriptional changes induced by bevacizumab combination therapy in responding and non-responding recurrent glioblastoma patients

    Bevacizumab combined with chemotherapy produces clinical durable response in 25–30% of recurrent glioblastoma patients. This group of patients has shown improved survival and quality of life. The aim of this s...

    Thomas Urup, Line Mærsk Staunstrup, Signe Regner Michaelsen, Kristoffer Vitting-Seerup, Marc Bennedbæk, Anders Toft, Lars Rønn Olsen, Lars Jønson, Shohreh Issazadeh-Navikas, Helle Broholm, Petra Hamerlik, Hans Skovgaard Poulsen and Ulrik Lassen

    BMC Cancer 2017 17:278

    Published on: 18 April 2017

  3. Research article

    The treatment of primary mediastinal large B-cell lymphoma: a two decades monocentric experience with 98 patients

    The purpose of this study is to investigate the most suitable first-line approach and the best combination treatment for primary mediastinal large B-cell lymphoma (PMLBCL) as they have been matter of debate fo...

    Alessandro Broccoli, Beatrice Casadei, Vittorio Stefoni, Cinzia Pellegrini, Federica Quirini, Lorenzo Tonialini, Alice Morigi, Miriam Marangon, Lisa Argnani and Pier Luigi Zinzani

    BMC Cancer 2017 17:276

    Published on: 17 April 2017

  4. Research article

    Prognostic value of pretreatment standardized uptake value of F-18-fluorodeoxyglucose PET in patients with gastric cancer: a meta-analysis

    F-18- fluorodeoxyglucose Positron emission tomography (18FDG-PET) has been widely used in clinical practice. However, the prognostic value of the pretreatment standardized uptake value (SUV) for patients with gas...

    Zhonghua Wu, Junhua Zhao, Peng Gao, Yongxi Song, Jingxu Sun, Xiaowan Chen, Bin Ma and Zhenning Wang

    BMC Cancer 2017 17:275

    Published on: 17 April 2017

  5. Research article

    Serum low-density lipoprotein and low-density lipoprotein expression level at diagnosis are favorable prognostic factors in patients with small-cell lung cancer (SCLC)

    Patients with small-cell lung cancer (SCLC) patients demonstrate varied survival outcomes. Previous studies have reported that lipoproteins are associated with prognosis in various cancers; however, the role o...

    Ting Zhou, Jianhua Zhan, Wenfeng Fang, Yuanyuan Zhao, Yunpeng Yang, Xue Hou, Zhonghan Zhang, Xiaobo He, Yaxiong Zhang, Yan Huang and Li Zhang

    BMC Cancer 2017 17:269

    Published on: 14 April 2017

  6. Case report

    Alpha–fetoprotein elevation in NUT midline carcinoma: a case report

    Nuclear protein in testis (NUT) midline carcinoma is a rarely diagnosed and potentially under-recognized type of squamous carcinoma that is considered one of the most aggressive human solid tumors. Alpha-fetop...

    Lorenzo D’Ambrosio, Erica Palesandro, Marina Moretti, Giuseppe Pelosi, Alessandra Fabbri, Fabrizio Carnevale Schianca, Massimo Aglietta and Giovanni Grignani

    BMC Cancer 2017 17:266

    Published on: 13 April 2017

  7. Research article

    Systemic therapy in younger and elderly patients with advanced biliary cancer: sub-analysis of ABC-02 and twelve other prospective trials

    Outcomes in younger (<40 years) and elderly (≥70 years) patients with advanced biliary cancer (ABC) receiving palliative chemotherapy are unclear. This study assessed outcomes in those receiving monotherapy or...

    Mairéad Geraldine McNamara, John Bridgewater, Andre Lopes, Harpreet Wasan, David Malka, Lars Henrik Jensen, Takuji Okusaka, Jennifer J. Knox, Dorothea Wagner, David Cunningham, Jenny Shannon, David Goldstein, Markus Moehler, Tanios Bekaii-Saab and Juan W. Valle

    BMC Cancer 2017 17:262

    Published on: 12 April 2017

  8. Research article

    Cost-effectiveness of response evaluation after chemoradiation in patients with advanced oropharyngeal cancer using 18F–FDG-PET-CT and/or diffusion-weighted MRI

    Considerable variation exists in diagnostic tests used for local response evaluation after chemoradiation in patients with advanced oropharyngeal cancer. The yield of invasive examination under general anesthe...

    Marjolein JE Greuter, Charlotte S Schouten, Jonas A Castelijns, Pim de Graaf, Emile FI Comans, Otto S Hoekstra, Remco de Bree and Veerle MH Coupé

    BMC Cancer 2017 17:256

    Published on: 11 April 2017

  9. Research article

    Sidedness is prognostic in locoregional colon cancer: an analysis of 9509 Australian patients

    Right sided colon cancer (RsCC) is proposed to be a distinct disease entity to left sided colon cancer (LsCC). We seek to confirm primary tumour location as an independent prognostic factor in locoregional col...

    Daniel Brungs, Morteza Aghmesheh, Paul de Souza, Weng Ng, Wei Chua, Martin Carolan, Philip Clingan, Emma Healey, June Rose, Tameika Tubaro and Marie Ranson

    BMC Cancer 2017 17:251

    Published on: 8 April 2017

  10. Case report

    Myoepithelial carcinoma with RB1 mutation: remarkable chemosensitivity to carcinoma of unknown origin therapy

    Myoepithelial carcinoma of soft tissue is a rare, malignant neoplasm that is morphologically and immunophenotypically similar to its counterpart in salivary gland. It demonstrates myoepithelial differentiation...

    Timothy M. Hoggard, Evita Henderson-Jackson, Marilyn M. Bui, Jamie Caracciolo, Jamie K. Teer, Sean Yoder, Odion Binitie, Ricardo J. Gonzalez, Andrew S. Brohl and Damon R. Reed

    BMC Cancer 2017 17:250

    Published on: 8 April 2017

  11. Research article

    The efficacy and safety of CapeOX plus bevacizumab therapy followed by capecitabine plus bevacizumab maintenance therapy in patients with metastatic colorectal cancer: a multi-center, single-arm, phase II study (CCOG-0902)

    The aim of this study was to evaluate the efficacy and safety of CapeOX plus bevacizumab with a planned oxaliplatin stop-and-go strategy in Japanese patients with metastatic colorectal cancer (mCRC).

    Goro Nakayama, Kiyoshi Ishigure, Hiroyuki Yokoyama, Keisuke Uehara, Hiroshi Kojima, Akiharu Ishiyama, Naomi Hayashi, Nao Takano, Norifumi Hattori, Daisuke Kobayashi, Chie Tanaka, Masamichi Hayashi, Mitsuro Kanda, Suguru Yamada, Hiroyuki Sugimoto, Masahiko Koike…

    BMC Cancer 2017 17:243

    Published on: 4 April 2017

  12. Research article

    Distribution of Ki-67 values within HER2 & ER/PgR expression variants of ductal breast cancers as a potential link between IHC features and breast cancer biology

    Unexpected differences in Ki-67 values among HER2 & ER/PgR defined subgroups were found. This study aims to detect possible subdivisions beyond the conventional breast cancer types.

    Sven Kurbel, Branko Dmitrović, Ksenija Marjanović, Damir Vrbanec and Antonije Juretić

    BMC Cancer 2017 17:231

    Published on: 29 March 2017

  13. Research article

    Amplification and up-regulation of MIR30D was associated with disease progression of cervical squamous cell carcinomas

    Cervical squamous cell carcinoma (CSCC) is the most frequent type among cervical cancers. Although the altered miRNA miR-30d expression and the amplified chromosome locus of MIR30D, 8q24, have been reported in...

    You Zhou, Yinghua Hao, Yuxia Li, Ruizhen Li, Ruifang Wu, Shubin Wang and Zhengyu Fang

    BMC Cancer 2017 17:230

    Published on: 29 March 2017

  14. Research article

    Can we use gonadotropin plasma concentration as surrogate marker for BMI-related incomplete estrogen suppression in breast cancer patients receiving anastrozole?

    BMI has been suggested to impact on estrogenic activity in patients receiving anastrozole resulting in a reduced treatment efficacy in obese women. Current evidence in this regard is controversially discussed....

    A. Oberguggenberger, V. Meraner, M. Sztankay, B. Beer, G. Weigel, H. Oberacher, G. Kemmler, T. Czech, B. Holzner, L. Wildt, B. Sperner-Unterweger, M. Daniaux and M. Hubalek

    BMC Cancer 2017 17:226

    Published on: 28 March 2017

Previous Page Page 1 of 15 Next Page

Can't find what you are looking for?

The following sections have not yet been added to this new-look site. In the meantime you can still view them on our old site.