Epidemiology, prevention and public health

Section edited by Manami Inoue

This section aims to consider publications which focus on all aspects of cancer epidemiology including risk factors for disease initiation and development, social determinants, environmental, behavioural, and occupational correlates, and the impact of health policies, practices and interventions on the community.

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  1. Research article

    Effect of genetic variants and traits related to glucose metabolism and their interaction with obesity on breast and colorectal cancer risk among postmenopausal women

    Impaired glucose metabolism–related genetic variants and traits likely interact with obesity and related lifestyle factors, influencing postmenopausal breast and colorectal cancer (CRC), but their interconnect...

    Su Yon Jung, Eric M. Sobel, Jeanette C. Papp and Zuo-Feng Zhang

    BMC Cancer 2017 17:290

    Published on: 26 April 2017

  2. Research article

    Regular recreational physical activity and risk of head and neck cancer

    Although substantial evidence supports a 20–30% risk reduction of colon cancer, breast cancer, and endometrial cancer by physical activity (PA), the evidence for head and neck cancer (HNC) is limited. Three pu...

    Chen-Lin Lin, Wei-Ting Lee, Chun-Yen Ou, Jenn-Ren Hsiao, Cheng-Chih Huang, Jehn-Shyun Huang, Tung-Yiu Wong, Ken-Chung Chen, Sen-Tien Tsai, Sheen-Yie Fang, Tze-Ta Huang, Jiunn-Liang Wu, Yuan-Hua Wu, Wei-Ting Hsueh, Chia-Jui Yen, Yu-Hsuan Lai…

    BMC Cancer 2017 17:286

    Published on: 21 April 2017

  3. Study protocol

    A protocol for a cluster-randomized controlled trial of a self-help psycho-education programme to reduce diagnosis delay in women with breast cancer symptoms in Indonesia

    Breast cancer (BC) is the most frequent cancer occurring in women across the world. Its mortality rate in low-middle income countries (LMICs) is higher than in high-income countries (HICs), and in Indonesia BC...

    Hari Setyowibowo, Marit Sijbrandij, Aulia Iskandarsyah, Joke A. M. Hunfeld, Sawitri S. Sadarjoen, Dharmayanti F. Badudu, Drajat R. Suardi and Jan Passchier

    BMC Cancer 2017 17:284

    Published on: 20 April 2017

  4. Research article

    Overview of cancer incidence and mortality among people living with HIV/AIDS in British Columbia, Canada: Implications for HAART use and NADM development

    The objective of this study is to evaluate the incidence of non-AIDS defining malignancies (NADMs) among people living with HIV/AIDS (PLWHA) in British Columbia, focusing on clinical correlates, highly active ...

    Connie G. Chiu, Danielle Smith, Kate A. Salters, Wendy Zhang, Steve Kanters, David Milan, Julio S.G. Montaner, Andy Coldman, Robert S. Hogg and Sam M. Wiseman

    BMC Cancer 2017 17:270

    Published on: 14 April 2017

  5. Research article

    Adjuvant treatment recommendations for patients with ER-positive/HER2-negative early breast cancer by Swiss tumor boards using the 21-gene recurrence score (SAKK 26/10)

    To evaluate the effect of Recurrence Score® results (RS; Oncotype DX® multigene assay ODX) on treatment recommendations by Swiss multidisciplinary tumor boards (TB).

    Bernhard C. Pestalozzi, Christoph Tausch, Konstantin J. Dedes, Christoph Rochlitz, Stefan Zimmermann, Roger von Moos, Ralph Winterhalder, Thomas Ruhstaller, Andreas Mueller, Katharina Buser, Markus Borner, Urban Novak, Catrina Uhlmann Nussbaum, Bettina Seifert, Martin Bigler, Vincent Bize…

    BMC Cancer 2017 17:265

    Published on: 13 April 2017

  6. Research article

    Effect of individualized communication skills training on physicians’ discussion of clinical trials in oncology: results from a randomized controlled trial

    Discussing randomized clinical trials (RCTs) with cancer patients is one of the most challenging communication tasks a physician faces. Only two prior Communication Skills Trainings (CSTs) focused on RCTs in o...

    Alexander Wuensch, Tanja Goelz, Gabriele Ihorst, Darcey D. Terris, Hartmut Bertz, Juergen Bengel, Michael Wirsching and Kurt Fritzsche

    BMC Cancer 2017 17:264

    Published on: 13 April 2017

  7. Research article

    Glucose and lipoprotein biomarkers and breast cancer severity using data from the Swedish AMORIS cohort

    The lipid and glucose metabolisms are postulated as possible intermediary mechanisms in linking obesity and breast cancer (BC). Links between serum lipid and glucose biomarkers and BC risk has been observed in...

    Jennifer C Melvin, Hans Garmo, Lars Holmberg, Niklas Hammar, Göran Walldius, Ingmar Jungner, Mats Lambe and Mieke Van Hemelrijck

    BMC Cancer 2017 17:246

    Published on: 4 April 2017

  8. Research article

    Case management to increase quality of life after cancer treatment: a randomized controlled trial

    Case management has been shown to be beneficial in phases of cancer screening and treatment. After treatment is completed, patients experience a loss of support due to reduced contact with medical professional...

    Nathalie Scherz, Irène Bachmann-Mettler, Corinne Chmiel, Oliver Senn, Nathalie Boss, Katarina Bardheci and Thomas Rosemann

    BMC Cancer 2017 17:223

    Published on: 28 March 2017

  9. Study protocol

    Design of a randomized controlled trial of physical training and cancer (Phys-Can) – the impact of exercise intensity on cancer related fatigue, quality of life and disease outcome

    Cancer-related fatigue is a common problem in persons with cancer, influencing health-related quality of life and causing a considerable challenge to society. Current evidence supports the beneficial effects o...

    Sveinung Berntsen, Neil K Aaronson, Laurien Buffart, Sussanne Börjeson, Ingrid Demmelmaier, Maria Hellbom, Pernille Hojman, Helena Igelström, Birgitta Johansson, Ronnie Pingel, Truls Raastad, Galina Velikova, Pernilla Åsenlöf and Karin Nordin

    BMC Cancer 2017 17:218

    Published on: 27 March 2017

  10. Research article

    Characterizing and prognosticating chronic lymphocytic leukemia in the elderly: prospective evaluation on 455 patients treated in the United States

    Median age at diagnosis of patients with chronic lymphocytic leukemia (CLL) is > 70 years. However, the majority of clinical trials do not reflect the demographics of CLL patients treated in the community. We ...

    Chadi Nabhan, Anthony Mato, Christopher R. Flowers, David L. Grinblatt, Nicole Lamanna, Mark A. Weiss, Matthew S. Davids, Arlene S. Swern, Shriya Bhushan, Kristen Sullivan, E. Dawn Flick, Pavel Kiselev and Jeff P. Sharman

    BMC Cancer 2017 17:198

    Published on: 16 March 2017

  11. Study protocol

    iCanADAPT Early protocol: randomised controlled trial (RCT) of clinician supervised transdiagnostic internet-delivered cognitive behaviour therapy (iCBT) for depression and/or anxiety in early stage cancer survivors -vs- treatment as usual

    This RCT with two parallel arms will evaluate the efficacy of an internet-delivered transdiagnostic cognitive behavioural therapy (iCBT) intervention for the treatment of clinical depression and/or anxiety in ...

    M. J. Murphy, J. M. Newby, P. Butow, L. Kirsten, K. Allison, S. Loughnan, M. A. Price, J. Shaw, H. Shepherd, J. Smith and G. Andrews

    BMC Cancer 2017 17:193

    Published on: 15 March 2017

  12. Study protocol

    Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT®-Lung Test (ECLS): study protocol for a randomized controlled trial

    Lung cancer is the most common cause of cancer related death worldwide. The majority of cases are detected at a late stage when prognosis is poor. The EarlyCDT®-Lung Test detects autoantibodies to abnormal cel...

    F. M. Sullivan, Eoghan Farmer, Frances S. Mair, Shaun Treweek, Denise Kendrick, Cathy Jackson, Chris Robertson, Andrew Briggs, Colin McCowan, Laura Bedford, Ben Young, Kavita Vedhara, Stephanie Gallant, Roberta Littleford, John Robertson, Herb Sewell…

    BMC Cancer 2017 17:187

    Published on: 11 March 2017

  13. Research article

    A survey to determine usual care after cancer treatment within the United Kingdom national health service

    Approximately one third of cancer survivors in the United Kingdom face ongoing and debilitating psychological and physical symptoms related to poor quality of life. Very little is known about current post-canc...

    M. Duncan, J. Deane, P. D. White, D. Ridge, R. Roylance, A. Korszun, T. Chalder, K. S. Bhui, M. A. Thaha and L. Bourke

    BMC Cancer 2017 17:186

    Published on: 11 March 2017

  14. Research article

    Receiver operating characteristic analysis of prediction for gastric cancer development using serum pepsinogen and Helicobacter pylori antibody tests

    Chronic Helicobacter pylori infection plays a central role in the development of gastric cancer as shown by biological and epidemiological studies. The H. pylori antibody and serum pepsinogen (PG) tests have been...

    Chisato Hamashima, Shizuka Sasazuki, Manami Inoue and Shoichiro Tsugane

    BMC Cancer 2017 17:183

    Published on: 9 March 2017

  15. Research article

    Impact of a combined multimodal-aerobic and multimodal intervention compared to standard aerobic treatment in breast cancer survivors with chronic cancer-related fatigue - results of a three-armed pragmatic trial in a comprehensive cohort design

    Cancer-related fatigue (CRF) and insomnia are major complaints in breast cancer survivors (BC). Aerobic training (AT), the standard therapy for CRF in BC, shows only minor to moderate treatment effects. Other ...

    Matthias Kröz, Marcus Reif, Augustina Glinz, Bettina Berger, Andreas Nikolaou, Roland Zerm, Benno Brinkhaus, Matthias Girke, Arndt Büssing and Christoph Gutenbrunner

    BMC Cancer 2017 17:166

    Published on: 2 March 2017

  16. Research article

    Life tables for global surveillance of cancer survival (the CONCORD programme): data sources and methods

    We set out to estimate net survival trends for 10 common cancers in 279 cancer registry populations in 67 countries around the world, as part of the CONCORD-2 study. Net survival can be interpreted as the prop...

    Devon Spika, Finian Bannon, Audrey Bonaventure, Laura M Woods, Rhea Harewood, Helena Carreira, Michel P Coleman and Claudia Allemani

    BMC Cancer 2017 17:159

    Published on: 27 February 2017

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