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Inhibition of the JAK2/STAT3 pathway in ovarian cancer results in the loss of cancer stem cell-like characteristics and a reduced tumor burden

  • Khalid Abubaker1, 2,
  • Rodney B Luwor3,
  • Hongjian Zhu3,
  • Orla McNally1, 4,
  • Michael A Quinn1, 4,
  • Christopher J Burns5,
  • Erik W Thompson2, 6,
  • Jock K Findlay1, 4, 7 and
  • Nuzhat Ahmed1, 2, 4, 7Email author
BMC Cancer201414:317

DOI: 10.1186/1471-2407-14-317

Received: 8 November 2013

Accepted: 23 April 2014

Published: 6 May 2014

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
8 Nov 2013 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
26 Nov 2013 Author responded Author comments - Nuzhat Ahmed
Resubmission - Version 3
26 Nov 2013 Submitted Manuscript version 3
7 Mar 2014 Reviewed Reviewer Report - Carmela Ricciardelli
7 Mar 2014 Reviewed Reviewer Report - Claudia Lengerke
11 Apr 2014 Author responded Author comments - Nuzhat Ahmed
Resubmission - Version 4
11 Apr 2014 Submitted Manuscript version 4
16 Apr 2014 Author responded Author comments - Nuzhat Ahmed
Resubmission - Version 5
16 Apr 2014 Submitted Manuscript version 5
22 Apr 2014 Author responded Author comments - Nuzhat Ahmed
Resubmission - Version 6
22 Apr 2014 Submitted Manuscript version 6
Publishing
23 Apr 2014 Editorially accepted
6 May 2014 Article published 10.1186/1471-2407-14-317

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article.. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Women’s Cancer Research Centre, Royal Women’s Hospital
(2)
Department of Surgery, St Vincent’s Hospital, University of Melbourne
(3)
Department of Surgery, University of Melbourne, Royal Melbourne Hospital
(4)
Department of Obstetrics and Gynaecology, University of Melbourne
(5)
Walter and Eliza Hall Institute of Medical Research
(6)
St Vincent’s Institute
(7)
Prince Henry’s Institute of Medical Research

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