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Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer

  • Patrick C O´Leary1,
  • Sarah A Penny1,
  • Roisin T Dolan1, 6,
  • Catherine M Kelly1,
  • Stephen F Madden3,
  • Elton Rexhepaj1,
  • Donal J Brennan1,
  • Amanda H McCann1, 2,
  • Fredrik Pontén4,
  • Mathias Uhlén5,
  • Radoslaw Zagozdzon1,
  • Michael J Duffy2, 7,
  • Malcolm R Kell6,
  • Karin Jirström8 and
  • William M Gallagher1Email author
Contributed equally
BMC Cancer201313:175

DOI: 10.1186/1471-2407-13-175

Received: 21 November 2012

Accepted: 19 March 2013

Published: 2 April 2013

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
21 Nov 2012 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
Resubmission - Version 3
Submitted Manuscript version 3
Resubmission - Version 4
Submitted Manuscript version 4
Resubmission - Version 5
Submitted Manuscript version 5
26 Nov 2012 Author responded Author comments - Patrick O'Leary
Resubmission - Version 6
26 Nov 2012 Submitted Manuscript version 6
6 Dec 2012 Reviewed Reviewer Report - Stefan Willems
25 Dec 2012 Reviewed Reviewer Report - Sunil Badve
Resubmission - Version 7
Submitted Manuscript version 7
19 Mar 2013 Editorially accepted
2 Apr 2013 Article published 10.1186/1471-2407-13-175

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

UCD School of Biomolecular and Biomedical Science, UCD Conway Institute of Biomolecular and Biomedical Science, University College Dublin
UCD School of Medicine and Medical Science, University College Dublin
Molecular Therapeutics for Cancer Ireland, National Institute for Cellular Biotechnology, Dublin City University
Department of Pathology, University Hospital of Uppsala
Royal Institute of Technology
Department of Breast & Endocrine Surgery, Mater Misericordiae University Hospital
UCD Clinical Research Centre, St. Vincent’s University Hospital
Division of Pathology, Department of Clinical Sciences, Lund University, Skåne University Hospital