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Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs

  • Shruti U Gandhy1,
  • KyoungHyun Kim2,
  • Lesley Larsen3,
  • Rhonda J Rosengren4 and
  • Stephen Safe2, 5Email author
BMC Cancer201212:564

DOI: 10.1186/1471-2407-12-564

Received: 13 April 2012

Accepted: 23 November 2012

Published: 30 November 2012

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
13 Apr 2012 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
Resubmission - Version 3
Submitted Manuscript version 3
14 Aug 2012 Reviewed Reviewer Report - Santi Prasad Sinha Babu
27 Sep 2012 Reviewed Reviewer Report - Sekhar Majumdar
8 Nov 2012 Author responded Author comments - Stephen Safe
Resubmission - Version 4
8 Nov 2012 Submitted Manuscript version 4
23 Nov 2012 Editorially accepted
30 Nov 2012 Article published 10.1186/1471-2407-12-564

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

College of Medicine, Texas A&M Health Sciences Center
Institute of Biosciences and Technology, Texas A&M Health Science Center
Department of Chemistry, University of Otago
Department of Pharmacology and Toxicology, University of Otago
Department of Veterinary Physiology and Pharmacology