Open Access

Erratum to:Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas

  • Yosuke Hashimoto1,
  • Marek Skacel2,
  • Ian C Lavery3,
  • Abir L Mukherjee4,
  • Graham Casey3, 4, 5 and
  • Josephine C Adams1, 2, 5Email author
BMC Cancer201111:488

DOI: 10.1186/1471-2407-11-488

Received: 15 November 2011

Accepted: 21 November 2011

Published: 21 November 2011

The original article was published in BMC Cancer 2006 6:241

Correction [1]: It was recently brought to our attention that, although the statistical analyses in Table four had passed the original peer-review of this paper, the risk ratio and value of the lower 95% confidence interval for some of the variables in Table four were not consistent with the p values. We have repeated the multi-variant statistical analysis of the original data with StatView software. This analysis produced different values for the risk ratios and 95% confidence intervals for variables other than age. The corrected Table four is presented below (table 1). The p values are unchanged, thus the original conclusions of the article are not altered.
Table 1

Corrected table four

Table 4a. Cox's proportional hazard analysis in stage I-IV patients

Variables

Risk ratio (95% confidence Interval)

p

Age (≥ 65 yrs)

1.618 (0/944-2.774)

0.080

Gender (male)

1.626 (0.965-2.740)

0.068

Lymph node metastasis (N1, 2)

0.253 (0.146-0.439)

< 0.001*

Distant metastasis (M1)

0.581 (0.317-1.066)

0.797

Tumour location (distal)

0.963 (0.550-1.686)

0.894

Fascin (high)

0.548 (0.272-1.104)

0.925

Table 4b. Cox's proportional hazard analysis in stage III/IV patients

Variable

Risk ratio (95% confidence Interval)

p

Age (> 65 yrs)

1.259 (0.683-2.318)

0.460

Gender (male)

1.659 (0.886-3.108)

0.114

Lymph node metastasis (N1, 2)

1.032 (0.358-2.972)

0.934

Distant metastasis (M1)

0.803 (0.381-1.697)

0.566

Tumour location (distal)

0.683 (0.362-1.289)

0.240

Fascin (high)

0.435 (0.197-0.957)

0.039*

Notes

Authors’ Affiliations

(1)
Department of Cell Biology, Lerner Research Institute, The Cleveland Clinic
(2)
Department of Anatomic Pathology, The Cleveland Clinic
(3)
Department of Colorectal Surgery, The Cleveland Clinic
(4)
Department of Cancer Biology, Lerner Research Institute, The Cleveland Clinic
(5)
Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, The Cleveland Clinic

References

  1. Hashimoto Y, Skacel M, Lavery IC, Mukherjee AL, Casey G, Adams JC: Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas. BMC Cancer. 2006, 6: 241-10.1186/1471-2407-6-241.View ArticlePubMedPubMed CentralGoogle Scholar
  2. Pre-publication history

    1. The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-2407/11/488/prepub

Copyright

© Hashimoto et al; licensee BioMed Central Ltd. 2011

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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