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Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin

  • Manuela Pinheiro1,
  • Terje Ahlquist2, 3,
  • Stine A Danielsen2, 3,
  • Guro E Lind2, 3,
  • Isabel Veiga1,
  • Carla Pinto1,
  • Vera Costa1,
  • Luís Afonso4,
  • Olga Sousa5,
  • Maria Fragoso6,
  • Lúcio Santos7,
  • Rui Henrique4, 9,
  • Paula Lopes4,
  • Carlos Lopes4, 9,
  • Ragnhild A Lothe2, 3, 8 and
  • Manuel R Teixeira1, 3, 9Email author
BMC Cancer201010:587

DOI: 10.1186/1471-2407-10-587

Received: 12 December 2009

Accepted: 27 October 2010

Published: 27 October 2010

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
12 Dec 2009 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
9 Feb 2010 Reviewed Reviewer Report - Konrad Kölble
23 Feb 2010 Reviewed Reviewer Report - Guido Plotz
20 Apr 2010 Author responded Author comments - Manuel R Teixeira
Resubmission - Version 3
20 Apr 2010 Submitted Manuscript version 3
11 May 2010 Reviewed Reviewer Report - Guido Plotz
Resubmission - Version 4
Submitted Manuscript version 4
Publishing
27 Oct 2010 Editorially accepted
27 Oct 2010 Article published 10.1186/1471-2407-10-587

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Department of Genetics, Portuguese Oncology Institute - Porto, Rua Dr. António Bernardino Almeida
(2)
Department of Cancer Prevention, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital
(3)
Centre for Cancer Biomedicine, University of Oslo
(4)
Department of Pathology, Portuguese Oncology Institute - Porto, Rua Dr. António Bernardino Almeida
(5)
Department of Radiotherapy, Portuguese Oncology Institute - Porto, Rua Dr. António Bernardino Almeida
(6)
Department of Oncology, Portuguese Oncology Institute - Porto, Rua Dr. António Bernardino Almeida
(7)
Department of Surgery, Portuguese Oncology Institute - Porto, Rua Dr. António Bernardino Almeida
(8)
Faculty of Medicine, University of Oslo
(9)
Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto

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