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The INSIG2 rs7566605 polymorphism is not associated with body mass index and breast cancer risk

  • Daniele Campa1,
  • Anika Hüsing1,
  • James D McKay2,
  • Olga Sinilnikova3,
  • Ulla Vogel4,
  • Anne Tjønneland5,
  • Kim Overvad6,
  • Jakob Stegger7,
  • Françoise Clavel-Chapelon8,
  • Nathalie Chabbert-Buffet8,
  • Guy Fagherazzi8,
  • Antonia Trichopoulou9, 10,
  • Dimosthenis Zylis9,
  • Erifili Oustoglou10,
  • Sabine Rohrmann1,
  • Birgit Teucher1,
  • Eva Fisher11,
  • Heiner Boeing11,
  • Giovanna Masala12,
  • Vittorio Krogh13,
  • Carlotta Sacerdote14,
  • Salvatore Panico15,
  • Rosario Tumino16,
  • N Charlotte Onland-Moret17,
  • Carla H van Gils17,
  • H Bas Bueno-de-Mesquita18,
  • Eiliv Lund19,
  • María Dolores Chirlaque20, 26,
  • Núria Sala21,
  • José Ramon Quirós22,
  • Eva Ardanaz23,
  • Pilar Amiano24, 26,
  • Esther Molina-Montes25, 26,
  • Göran Hallmans27,
  • Per Lenner27,
  • Ruth C Travis28,
  • Timothy J Key28,
  • Nick Wareham29,
  • Kay-Tee Khaw29,
  • Sabina Rinaldi2,
  • Nadia Slimani2,
  • Veronique Chajes2,
  • Afshan Siddiq30,
  • Elio Riboli30,
  • Rudolf Kaaks1 and
  • Federico Canzian1Email author
BMC Cancer201010:563

DOI: 10.1186/1471-2407-10-563

Received: 20 January 2010

Accepted: 18 October 2010

Published: 18 October 2010

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
20 Jan 2010 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
17 Mar 2010 Reviewed Reviewer Report - Tanya Agurs-Collins
30 Apr 2010 Reviewed Reviewer Report - Niloufar (Neely) Kazerouni
24 Jun 2010 Author responded Author comments - Daniele Campa
Resubmission - Version 3
24 Jun 2010 Submitted Manuscript version 3
26 Jul 2010 Reviewed Reviewer Report - Tanya Agurs-Collins
4 Aug 2010 Reviewed Reviewer Report - Niloufar (Neely) Kazerouni
11 Oct 2010 Author responded Author comments - Daniele Campa
Resubmission - Version 4
11 Oct 2010 Submitted Manuscript version 4
18 Oct 2010 Editorially accepted
18 Oct 2010 Article published 10.1186/1471-2407-10-563

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

German Cancer Research Center (DKFZ)
International Agency for Research on Cancer
Hospices Civils de Lyon/Centre Léon Bérard, UMR5201 CNRS-Université Claude Bernard
National Food Institute Technical University of Denmark
Danish Cancer Society
Aarhus University Hospital
Department of Cardiology, Cardiovascular Research Centre, Aalborg Hospital, Aarhus University Hospital
Institut Gustave Roussy
WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School
Hellenic Health Foundation
German Institute of Human Nutrition
Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute (ISPO)
Istituto Nazionale dei Tumori (IRCCS)
CPO Piemonte
Department of Clinical and Experimental Medicine Federico II University
Azienda Ospedaliera "Civile M.P.Arezzo" Ragusa
Julius Center, University Medical Center
National Institute for Public Health and the Environment
Institute of Community Medicine University of Tromsø
Murcia Regional Health Council
Catalan Institute of Oncology
Consejería de Salud y Servicios Sanitarios Principado de Asturias
Public Health Institute of Navarra
Public Health Department of Gipuzkoa
Andalusian School of Public Health
CIBER de Epidemiología y Salud Pública (CIBERESP)
Umeå University
Cancer Epidemiology Unit, Nuffield Department of Clinical Medicine, University of Oxford
University of Cambridge
Imperial College